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CHOLECALCIFEROL
SynDRA canonical compound SYN0003318 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CYP2J2 | VDR |
|---|
| Indication | vitamin D deficiency |
|---|
| Disease area | endocrinology |
|---|
All known targets
- VDR
- CYP27A1
- CYP27B1
- CYP2J2
- CYP2R1
- GLRA1
- Vdr
Mechanisms of action (all sources)
- VDR AGONIST
- Vitamin D receptor agonist
- VDR BINDER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- ACHE
- MAPT
- OPRM1
- OPRK1
- OPRD1
- NR3C1
- NR1H4
- NPY2R
- NPY1R
- NFE2L2
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- PDE4A
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- PDE3A
- PDE5A
- HRH2
- SLC6A4
- USP1
- UGT1A4
- UGT1A1
- TST
- TP53
- THRB
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP3A4
- GEMI
- IFNG
- LOX15
- MDR1
- NF2L2
Drug classes
- Bone Density Conservation Agents
- Calcium-Regulating Hormones and Agents
- Micronutrients
- Vitamins
- Vitamin D
ATC classes
- A11C · VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO
- DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
Cross-references
Synonyms
- Decalcitrol
- FOSAMAX PLUS D
- INFUVITE ADULT
- INFUVITE PEDIATRIC
- INFUVITE PEDIATRIC (PHARMACY BULK PACKAGE)
- MULTIPLE VITAMINS INJECTION ADULT
- MULTIPLE VITAMINS INJECTION PEDIATRIC
- MULTIPLE VITAMINS INJECTION PEDIATRIC (PHARMACY BULK PACKAGE)
- colecalciferol
- Vitamin D3
- arachitol
- calciol
- calcirol
- Colecalciferol
- Vitamin d3
- 7-dehydrocholesterol, activated
- Colecalciferolum
- Delsterol
- Delta-d
- Deparal
- Ebivit
- Provitina
- Ricketon
- Vigantoletten
- Vitamin d (cholecalciferol)
- Vitamin d 3
- Vitamin d3 (as cholecalciferol)
- CHOLECALCIFEROL COMPONENT OF AK-R215 COLECALCIFEROL
- NSC-375571
- Accrete d3
- Aciferol d3
- Adcal-d3
- Biolife vitamin d3
- Cacit d3
- Calceos
- Calci-d
- Calcichew d3
- Calcichew d3 fte
Reported adverse events
- Hypervitaminosis A
- Rash
- Fracture
- Stevens-Johnson syndrome
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