← SynDRA
TYRPHOSTIN 47
SynDRA canonical compound SYN0003273 — structure-anchored drug synonym record
| Primary target(s) | EGFR |
|---|
| Mechanism of action | EGFR inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ERBB2
- ALDH1A1
- GLA
- TP53
- TDP1
- SYK
- RECQL
- POLK
- PKM
- NFKB1
- MAPT
- MAPK1
- KDM4E
- HSD17B10
- HPGD
- HIF1A
- GBA1
- ALOX12
- GAA
- DNM1
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- BRCA1
- BLM
- APEX1
- ALOX15B
- ALOX15
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADCY9
- CP1A2
- CP2CJ
- CP3A4
- CSF1R
- G3P
- LOX12
- LOX15
- MK01
- PHGDH
- RAPGEF3
- RPGF3
- TGM2
Drug classes
Cross-references
Synonyms
- TYRPHOSTIN-47
- tyrphostin AG213
- AG-213
- Tyrphostin AG 213
- RG 50864
- Tyrphostin RG50864
- alpha-Cyano-3,4-dihydroxythiocinnamamide
- 3,4-Dihydroxy-alpha-cyanothiocinnamide
- RG50864
- 2-Propenethioamide, 2-cyano-3-(3,4-dihydroxyphenyl)-
- 2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenethioamide
- HKQ7UDF4J7
- NSC-638083
- AG213
- RefChem:900826
- DTXCID801475292
- Tyrphostin A47
- (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide
- (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide
- 2-Propenethioamide, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)-
- 3,4-Dihydroxy-alpha-cyanothiocinnamamide
- 3,4-Dihydroxybenzylidenethioacetamide
- alpha-Cyano-(3,4-dihydroxy)thiocinnamide
- Tocris-0503
- BiomolKI_000014
- Lopac-T-7540
- BiomolKI2_000024
- AG213 (Tyrphostin 47)
- BMK1-C2
- BSPBio_001392
- T7540 (Tyrphostin 47)
- BDBM4363
- SCHEMBL5800282
- SCHEMBL14411466
- SCHEMBL29422960
- CHEBI:93703
- ZGHQGWOETPXKLY-XVNBXDOJSA-N
- HMS1361F14
Look up TYRPHOSTIN 47 in the interactive SynDRA portal →