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ALOISINE A
SynDRA canonical compound SYN0003263 — structure-anchored drug synonym record
| Primary target(s) | CDK2 |
|---|
| Mechanism of action | CFTR channel agonist |
|---|
All known targets
- CDK2
- CDK1
- CDK5
- GSK3A
- CCNA2
- CCNE1
- PTK2B
- ZAP70
Mechanisms of action (all sources)
- cyclin-dependent kinase inhibitor
- GSK-3 inhibitor
- CFTR channel agonist
- CDK1 INHIBITOR
- CDK2 INHIBITOR
- CDK5 INHIBITOR
- GSK3A INHIBITOR
- ZAP70 INHIBITOR
- PTK2B INHIBITOR
- CCNE1 INHIBITOR
- CCNA2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- MAPK8
- MAPK10
- CFTR
- STK33
- PIM1
- GSK3B
- CLK1
- MAPK9
- PRKCI
- PRKCH
- PDGFRA
- PDGFRB
- PDPK1
- PHKG2
- PRKD2
- PRKD1
- PIM2
- PIM3
- PKN2
- PRKCZ
- PLK1
- PLK2
- PLK3
- PLK4
- PBK
- PRKACA
- PRKCA
- PRKCB
- PRKCD
- PRKCE
- PRKCQ
- PRKCG
- PRKAA2
- PAK6
- PASK
- PRKX
- MARK1
- MARK2
- MELK
- MERTK
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CCNA1
- CCNB1
- CCNB2
- CCNB3
- CCNE2
- CDK5R1
- GEM
Cross-references
Synonyms
- 4-(7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol
- RP107
- 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE
- CHEMBL75680
- 7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
- RP-107
- ALH
- 4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol
- 1ung
- SCHEMBL80147
- BDBM7377
- GTPL5924
- AC1NS169
- 4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)-phenol
- CHEBI:93641
- CTK8D4068
- DTXSID30416115
- HMS3229A14
- RM-39
- BCP26893
- ZINC2540737
- ACT06534
- IN1539
- HSCI1_000219
- MFCD04973541
- AKOS005145972
- CCG-206814
- DB07364
- RTC-063070
- AJ-39131
- aloisine
- RefChem:883882
- Aloisine A RP107
- Aloisine A, RP107
- orb1705096
- SCHEMBL22758654
- GLXC-02529
- EBC-42023
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