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MEDETOMIDINE
SynDRA canonical compound SYN0003243 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ADRA2C |
|---|
| Mechanism of action | Adrenergic receptor agonist |
|---|
| Indication | sedative |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- ADRA2A
- ADRA2B
- ADRA2C
- ADRA1A
- ADRA1B
- ADRA1D
- Adra1a
- Adra1b
- Adra1d
- Adra2a
- Adra2b
- Adra2c
Mechanisms of action (all sources)
- Adrenergic receptor agonist
- ADRA2A AGONIST
- ADRA2A PARTIAL AGONIST
- ADRA2B FULL AGONIST
- ADRA2C AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- OPRD1
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MC4R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRK1
- HTR2A
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HTR2B
- HTR1A
- ADORA2A
- CHRM2
- ADORA3
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
- BDKRB2
- CCKAR
- CCKBR
- CHRM1
- CHRM3
- HRH3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Adrenergic Agents
- Adrenergic Agonists
- Adrenergic alpha-2 Receptor Agonists
- Adrenergic alpha-Agonists
- Analgesics
- Analgesics, Non-Narcotic
- Central Nervous System Agents
- Central Nervous System Depressants
- Hypnotics and Sedatives
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Sensory System Agents
Cross-references
Synonyms
- Placadine
- medetomidine hydrochloride
- (+/-)-Medetomidine
- dl-Medetomidine
- medetomidine HCl
- Medetomidina
- Domitor
- MR15E85MQM
- (+-)-4-(alpha,2,3-trimethylbenzyl)imidazole
- Medetomidinum
- CHEBI:48552
- RefChem:56412
- DTXCID1028233
- Medetomidinum [Latin]
- Medetomidina [Spanish]
- Medetomidine (INN)
- MEDETOMIDINE [INN]
- Medetomidine [INN:BAN]
- UNII-MR15E85MQM
- MFCD00864346
- MEDETOMIDINE [MI]
- Dexmedetomidine Impurity 38
- Domitor [veterinary] (TN)
- SCHEMBL26432
- SCHEMBL787407
- orb1909168
- SCHEMBL29945090
- MEDETOMIDINE [GREEN BOOK]
- HMS3651H20
- HMS5081O12
- MSK11009
- BDBM50036913
- EBC-68033
- MFCD24392996
- AKOS016010776
- AKOS037643760
- CS-0734
- FM45840
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