← SynDRA

ARTENIMOL

SynDRA canonical compound SYN0003214 — structure-anchored drug synonym record

All known targets

• ATP1A1
• CYP2B6
• CYP2C19
• CYP3A5

Mechanisms of action (all sources)

• DNA synthesis inhibitor
• ATP1A1 BINDER

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• PTGES2
• ABCB1
• CYP2B6
• CYP2C9
• CYP3A4
• HDAC1
• HDAC2
• HDAC3
• HDAC6

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• IFNG

Drug classes

• Anti-Infective Agents
• Antimalarials
• Antiparasitic Agents
• Antiprotozoal Agents
• antimalarial agent
• Antimalarial
• Anthelmintics
• Antineoplastic Agents
• Antiplatyhelmintic Agents
• Antiviral Agents
• Schistosomicides

ATC classes

• P01B · ANTIMALARIALS

Cross-references

• PubChem CID: 3000518
• ChEMBL: CHEMBL252518
• DrugBank: DB11638
• ChEBI: CHEBI:135921
• KEGG: D07362
• RxNorm: 2584841
• Wikipedia: Dihydroartemisinin
• TTD: D0N6FH

Synonyms

• dihydroartemisinin
• dihydroartemisinine
• dihydroqinghaosu
• alaxin
• cotecxin
• cotexin
• beta-Dihydroartemisinin
• Dihydroartemisinin
• .beta.-dihydroartemisinin
• Alaxin
• Artenimolum
• Cotecxin
• Cotexin
• Di-hydroqinghaosu
• Dihydroartemisinin, .beta.-
• Dihydroartemisinine
• Dihydroqinghaosu
• Dynamax
• Salaxin
• Santecxin
• GNF-PF-5634
• Artenimol component of eurartesim dihydroartemisinin
• Artemether related compound a
• Dihydroquinghaosu
• Dihydroquinghoasu
• VM3352
• Artenimol (INN)
• JAV-110
• (3R,5aS,6R,8aS,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10-ol
• [3R-(3.alpha.,5a.beta.,6.beta.,8a.beta.,9.alpha.,10.alpha.,12.beta.,12aR*)]-Decahydro-10-hydroxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4.3-j]-1,2-benzodioxepin
• 1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol(Dihydroartemisinin)
• (3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol
• Artenimol [INN]
• Dihydro Artemisinin
• (3r,5as,6r,8as,9r,10s,12r,12ar)-decahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano[4,3-j][1,2]benzodioxepin-10-ol
• 6A9O50735X
• (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-ol
• 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-ol, decahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-

Reported adverse events

• Aspartate aminotransferase increased
• Chills
• Fatigue
• Hypersensitivity
• Infection
• Insomnia
• Malaise
• Nasopharyngitis
• Palpitations
• Plasmodium falciparum infection
• Pruritus
• Rhinitis