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TRYPTANTHRIN
SynDRA canonical compound SYN0003200 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | ALOX5 | HGF | IDO1 | PTGS2 |
|---|
| Mechanism of action | cyclooxygenase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- IDO1 INHIBITOR
- cyclooxygenase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TDO2
- HDAC6
- IDO2
- NTRK2
- NTRK1
- ABCC2
- MBNL1
- TOP1
- TDP1
- SMAD3
- SLC2A1
- RAB9A
- PTH1R
- POLI
- NPC1
- NFE2L2
- MAPT
- ATAD5
- MAPK9
- MAPK8
- MAPK10
- LMNA
- KMT2A
- KAT2A
- HTT
- GMNN
- CYP3A4
- CYP2C9
- CYP2C19
- TOP2A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- CSTA
- GEMI
- HCRTR1
- HXA9
- I23O1
- MPI
- NR1I2
- NR5A2
- PAFA2
- PE2R2
- RAC1
- U17L5
- USP28
Cross-references
Synonyms
- GNF-PF-2691
- couroupitine a
- Indolo[2,1-b]quinazoline-6,12-dione
- Tryptanthrine
- Couroupitine a
- TCMDC-125859
- Indolo(2,1-b)quinazoline-6,12-dione
- MFCD00012073
- CHEBI:9768
- CHEMBL306946
- 4Y6E3F2U66
- NSC349447
- NSC 349447
- SR-01000521538
- Tryptantherin
- TRIPTANTRIN
- Indolo[2,12-dione
- Oprea1_754264
- 6,12-dihydro-6,12-dioxoindole(2,1-b)quinazoline
- MLS001049121
- UNII-4Y6E3F2U66
- GTPL8224
- SCHEMBL2426211
- ZINC33299
- DTXSID90157431
- Tryptanthrin, >=98% (HPLC)
- HMS2271H05
- AMY31414
- HY-N6607
- BDBM50240612
- s5686
- STK078931
- AKOS000671350
- CCG-208326
- NCGC00160337-01
- NCGC00160337-02
- DS-15687
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