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TOLMETIN
SynDRA canonical compound SYN0003185 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
| Indication | osteoarthritis | rheumatoid arthritis |
|---|
| Disease area | rheumatology |
|---|
All known targets
- PTGS2
- PTGS1
- AKR1B1
- Akr1b1
- CXCL8
- GLO1
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- PTGS2 INHIBITOR
- PTGS1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- FLT1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KCNH2
- KAT2A
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HPGD
- HMGCR
- HDAC6
- GMNN
- MMP1
- MMP9
- NPY1R
- PTPRC
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SIGMAR1
- PTAFR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Cyclooxygenase Inhibitors
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
- Nonsteroidal Anti-inflammatory Drug
ATC classes
- M02A · TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Cross-references
Synonyms
- TOLECTIN
- TOLECTIN 600
- TOLECTIN DS
- TOLMETIN SODIUM
- Tolectin 600
- Tolectin DS
- tolmetin sodium anhydrous
- tolmetine
- tolmetin sodium
- tolmetin sodium salt
- tolmetin sodium salt dihydrate
- Tolmetine
- Tolmetina
- MCN-2559
- Tolectin
- Tolmetino
- Tolmetinum
- Tolmetina [DCIT]
- McN-2559
- Tolectin (TN)
- Tolmetin Sodium, Dihydrate
- Tolmetine [INN-French]
- Tolmetino [INN-Spanish]
- Tolmetinum [INN-Latin]
- Tolmetin (USAN/INN)
- Tolmetin [USAN:BAN:INN]
- Acido 1-metil-5-(p-tolnil)-pirrol-2-acetico
- Acido 1-metil-5-(p-tolnil)-pirrol-2-acetico [Spanish]
- 1-Methyl-5-p-toluoylpyrrole-2-acetic acid
- 2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetic acid
- 5-(p-Toluoyl)-1-methylpyrrole-2-acetic acid
- MCN 2559
- D8K2JPN18B
- tolectin
- Pyrrole-2-acetic acid, 1-methyl-5-p-toluoyl-
- CHEBI:71941
- 5-22-06-00392 (Beilstein Handbook Reference)
- McN2559
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