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DIENESTROL
SynDRA canonical compound SYN0003170 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | ESR1 |
|---|
| Mechanism of action | estrogen receptor agonist |
|---|
| Indication | menopause |
|---|
| Disease area | endocrinology |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA3
- NR3C1
- ADRB2
- ADORA1
- MAPT
- OPRD1
- NR1I2
- NPY1R
- MLNR
- MC4R
- MC3R
- LMNA
- MAOA
- OPRM1
- KCNH2
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- OPRK1
- PDE4D
- PDE3A
- SLCO1B3
- UGT2B15
- UGT1A1
- TP53
- TDP1
- TBXA2R
- SNCA
- SMAD3
- SLCO1B1
- HRH2
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- RAPGEF4
- PTGS2
- PGR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- LOX12
- RPGF4
- RARA
- PRGR
- PPARG
- NSD2
- NR1H4
- NF2L2
- LOX15
- KSYK
- ANDR
- HSPB1
- GEMI
- GCR
- ESR2
- CP3A7
- CP3A4
- CP2D6
- CP2C9
- SYK
Drug classes
- Estrogens
- Estrogens, Non-Steroidal
- Hormones
ATC classes
Cross-references
Synonyms
- DV
- ESTRAGUARD
- cycladiene
- dienesterol
- dienoestrol
- estrodienol
- follidiene
- oestrodiene
- synestrol
- Dienestrol trans-form
- Cycladiene
- Dehydrostilbestrol
- Dienestrol, .alpha.-
- Dienoestrol
- Dienol
- Dinovex
- Estragard
- Estroral
- Follidiene
- Gynefollin
- Oestrasid
- Oestrodiene
- Oestroral
- Restrol
- Retalon
- NSC-59809
- Dv
- Estraguard
- Hormofemin
- Synestrol
- Agaldog
- Dehydrostilboestrol
- Dienesterol
- Dienestrolo
- Dienestrolum
- Dinestrol
- Estrodienol
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