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CANDESARTAN CILEXETIL
SynDRA canonical compound SYN0003157 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | AGTR1 |
|---|
| Mechanism of action | Angiotensin receptor antagonist |
|---|
| Indication | congestive heart failure | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- AGTR1
- ABCG2
- ADORA3
- ADRA2B
- ADRB3
- CYP2C9
- CYP3A4
- EGFR
- ERBB2
- NAE1
- POLH
- POLI
Mechanisms of action (all sources)
- Angiotensin receptor antagonist
- AGTR1 ANTAGONIST
- Type-1 angiotensin II receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1A
- SLCO1B3
- HTR2A
- NR1I2
- ESR1
- NR3C1
- OPRD1
- OPRM1
- PDE4D
- CNR1
- CHRM2
- SLCO1B1
- PGR
- HTR2B
- AGTR2
- ADRA1A
- TBXA2R
- MAPK1
- USP1
- NPY2R
- NPY1R
- MLNR
- MC4R
- MC3R
- USP2
- HTR5A
- UBE2M
- KDM4E
- KCNH2
- KAT2A
- HTR7
- HTR6
- MAOA
- TACR2
- TACR1
- RECQL
- TDP1
- SLC6A4
- SLC6A3
- TP53
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- KISSR
- TRHR
- RPGF4
- RPGF3
- RARA
- RAPGEF4
- RAPGEF3
- NF2L2
- GPX4
- CP19A
- GNRHR
- GLI3
- ESRRA
- CP3A7
- CP3A4
- CP2D6
- CP2C9
- UBP1
Drug classes
- Angiotensin 2 Receptor Antagonists
- Angiotensin 2 Receptor Blocker
- Angiotensin II Type 1 Receptor Blockers
- Angiotensin Receptor Antagonists
- Antihypertensive Agents
- Cardiovascular Agents
ATC classes
- ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), PLAIN
- ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS
- LIPID MODIFYING AGENTS, COMBINATIONS
Cross-references
Synonyms
- ATACAND
- ATACAND HCT
- Atacand
- CANDESARTAN CILEXETIL AND HYDROCHLOROTHIAZIDE
- TCV 116
- Candesartan 1-(((cyclohexyloxy)carbonyl)oxy)ethyl ester
- NSC-758697
- TCV-116
- Amias
- Ratacand
- candesartan-cilextil
- candesartan
- Blopress
- CV 11974
- NSC 759858
- CHEMBL1016
- S8Q36MD2XX
- CHEBI:3347
- NCGC00167474-01
- [3H]candesartan
- Candesartan [INN]
- CAS-139481-59-7
- SR-05000001447
- Candesartan (USAN/INN)
- UNII-S8Q36MD2XX
- Candesartan [USAN:INN:BAN]
- HSDB 7520
- Candesartan-[d5]
- Candesartan- Bio-X
- CANDEMORE
- CELEXETIL
- candesartan (Atacand)
- KS-5003
- Candesartan - Atacand
- CANDESARTAN [MI]
- TCV-116 (prodrug)
- CANDESARTAN [HSDB]
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