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VILOXAZINE
SynDRA canonical compound SYN0003121 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | SLC6A2 |
|---|
| Mechanism of action | Serotonin reuptake inhibitor |
|---|
| Indication | depression |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SLC6A2
- SLC6A4
- HTR2B
- SLC6A3
- Slc6a2
- Slc6a3
- Slc6a4
Mechanisms of action (all sources)
- Serotonin reuptake inhibitor
- SLC6A2 INHIBITOR
- Norepinephrine transporter inhibitor
- norepinephrine reuptake inhibitor
- SLC6A2 ANTAGONIST
- HTR2B ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1A
- ADRB2
- ACHE
- HTR3A
- MC3R
- MAOA
- KDR
- KCNH2
- HTR7
- HTR6
- HTR5A
- HTR2C
- MLNR
- HTR2A
- HRH3
- HRH2
- HRH1
- HDAC6
- GIPR
- MC4R
- NPY1R
- GCGR
- PDE6A
- TACR2
- TACR1
- SLC29A1
- SAMHD1
- PTGS2
- PTGS1
- PGR
- PDE4D
- NPY2R
- PDE4A
- PDE3A
- OPRM1
- OPRK1
- OPRD1
- NTSR1
- NR3C1
- GHSR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Norepinephrine Uptake Inhibitors
- Norepinephrine Reuptake Inhibitor
- Cytochrome P450 2D6 Inhibitors
- Cytochrome P450 1A2 Inhibitors
- Cytochrome P450 2B6 Inhibitors
- Cytochrome P450 3A4 Inhibitors
- Adrenergic Agents
- Adrenergic Uptake Inhibitors
- Antidepressive Agents
- Antidepressive Agents, Second-Generation
- Central Nervous System Agents
- Membrane Transport Modulators
ATC classes
Cross-references
Synonyms
- QELBREE
- Qelbree
- viloxazine hydrochloride
- emovit
- viloxazin
- viloxazine HCl
- ICI 58,834
- ICI 58834
- Viloxazina
- Viloxazin
- Viloxazine hydrochloride
- 2-((2-Ethoxyphenoxy)methyl)morpholine hydrochloride
- Vivalan
- Vicilan
- Emovit
- Viloxazine HCl
- 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride
- CCRIS 1915
- Viloxazine hydrochloride [USAN]
- Viloxacina clorhidrato [Spanish]
- EINECS 252-638-6
- 2-((2-ethoxyphenoxy)methyl)morpholinehydrochloride
- 2-((o-Ethoxyphenoxy)methyl)morpholine hydrochloride
- (+-)-2-(o-ethoxyphenoxymethyl)morpholine
- 5I5Y2789ZF
- Morpholine, 2-((2-ethoxyphenoxy)methyl)-
- 2-((2-ETHOXYPHENOXY)METHYL)MORPHOLINE
- 2-[(2-ethoxyphenoxy)methyl]morpholine
- Viloxazinum
- Morpholine, 2-[(2-ethoxyphenoxy)methyl]-
- RefChem:56627
- DTXCID0031683
- N06AX09
- ICI58,834
- 2-(2-Ethoxyphenoxymethyl)tetrahydro-1,4-oxazine
- Viloxazine (INN)
- VILOXAZINE [INN]
- Viloxazine [INN:BAN]
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