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AMIFOSTINE
SynDRA canonical compound SYN0003098 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | ALPPL2 | ENPP1 |
| Mechanism of action | reducing agent |
| Indication | renal toxicity |
| Disease area | nephrology |
All known targets
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- KCNH2
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- HTR6
- FLT1
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GHSR
- NPY1R
- NPY2R
- NR1I2
- NR3C1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SIGMAR1
- SAMHD1
- RGS4
Drug classes
- Protective Agents
- Radiation-Protective Agents
- reducing agent
ATC classes
- V03A · ALL OTHER THERAPEUTIC PRODUCTS
Cross-references
Synonyms
- ETHYOL
- Ethyol
- aminopropylaminoethyl thiophosphate
- ethiofos
- gammaphos
- WR-2721
- amifostine trihydrate
- Amifostina
- Amifostine trihydrate
- Amifostine anhydrous
- Ethiofos
- Ethiofos anhydrous
- Gammaphos
- NSC-296961
- NSC-758236
- WR-2721 TRIHYDRATE
- YM-08310
- Amifostine disulfide
- WR-1064
- WR-2721C
- Apaetp
- Aminopropylaminoethyl thiophosphate
- Ethiofos Anhydrous
- Amifostine Anhydrous
- YM 08310
- NSC 296961
- NSC296961
- Amifostinum
- ILA426L95O
- WR2721
- ({2-[(3-aminopropyl)amino]ethyl}sulfanyl)phosphonic acid
- CHEBI:2636
- DTXCID602585
- ((2-((3-aminopropyl)amino)ethyl)sulfanyl)phosphonic acid
- Cytofos
- RefChem:111980
- V03AF05
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