← SynDRA
DEFERIPRONE
SynDRA canonical compound SYN0003090 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | UGT1A6 |
|---|
| Mechanism of action | Chelating agent |
|---|
| Indication | iron overload | thalassemia | transfusional hemosiderosis |
|---|
| Disease area | hematology |
|---|
All known targets
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KDM2B
- KDM6A
- KDM2A
- DRD2
- KDM5C
- KDM4A
- KDM4E
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- ACHE
- MMP9
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- MMP1
- NPY1R
- HDAC6
- PTGS2
- TF
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
Drug classes
- Iron Chelating Activity
- Iron Chelator
- Chelating Agents
- Iron Chelating Agents
- Sequestering Agents
- Chelating agent
ATC classes
- V03A · ALL OTHER THERAPEUTIC PRODUCTS
Cross-references
Synonyms
- FERRIPROX
- Ferriprox
- deferione
- ferriprox
- Deferiprona
- Deferipron
- APO-066
- APO-66
- CP-20
- CP20
- DN-180-01-AF
- DN-18001AF
- L-1
- L1
- NSC-758880
- PL-1
- PL1
- Deferiprone lipomed
- Ferriprox (TN)
- 3-hydroxy-1,2-dimethylpyridin-4(1H)-one
- NSC 758880
- 4(1H)-Pyridinone, 3-hydroxy-1,2-dimethyl-
- 2BTY8KH53L
- deferiprone (ep monograph)
- 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
- 1,2-Dimethyl-3-hydroxy-4(1H)-pyridinone
- CHEBI:68554
- 4(1H)-Pyridinone, 1,2-dimethyl-3-hydroxy-
- 3-hydroxy-1,2-dimethyl-4- pyridinone
- 4(1H)-Pyridone, 3-hydroxy-1,2-dimethyl-
- DTXCID4020666
- DMOHPO
- HDMPP
- Deferipronum
- RefChem:57612
- V03AC02
- 3-hydroxy-1,2-dimethyl-4(1H)-pyridinone
Reported adverse events
- Neutropenia
- Abdominal pain
- Agranulocytosis
- Arthralgia
- Back pain
- Chromaturia
- Dyspepsia
- Headache
- Increased appetite
- Nausea
- Pain in extremity
- Vomiting
Look up DEFERIPRONE in the interactive SynDRA portal →