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DOXYLAMINE
SynDRA canonical compound SYN0003075 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HRH1 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
| Indication | sedative |
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| Disease area | neurology/psychiatry |
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All known targets
Mechanisms of action (all sources)
- Histamine receptor antagonist
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CHRM2
- ESR1
- ACHE
- SAMHD1
- MBNL1
- OPRM1
- PDE3A
- PDE4A
- PGR
- PTGS1
- SLC47A1
- KDR
- SLC47A2
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B3
- TBXA2R
- UGT1A4
- MAOA
- HTR2B
- KCNH2
- ADORA3
- ADRA1A
- ADRA2A
- AR
- ARSA
- BLM
- CHRM1
- DRD1
- DRD3
- EHMT2
- F2
- FEN1
- GMNN
- HDAC6
- HRH3
- HTR1A
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Histamine Receptor Antagonists
- Histamine Agents
- Histamine Antagonists
- Histamine H1 Antagonists
- Neurotransmitter Agents
- Antiemetics
- Central Nervous System Agents
- Gastrointestinal Agents
- Peripheral Nervous System Agents
- Antihistamine
ATC classes
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
Cross-references
Synonyms
- BENDECTIN
- BONJESTA
- Bonjesta
- DECAPRYN
- DICLEGIS
- DOXY-SLEEP-AID
- DOXYLAMINE SUCCINATE
- DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE
- Diclegis
- UNISOM
- Unisom
- (+/-)-Doxylamine
- doxylamine succinate
- Doxilamina
- Dossilamina
- Doxilminio
- Doxylaminum
- Dossilamina [DCIT]
- Diclectin (TN)
- Dolased (TN)
- Donormyl (TN)
- Dormidina (TN)
- Doxilminio [INN-Spanish]
- Doxylamine (INN)
- Doxylamine [INN:BAN]
- Doxylaminum [INN-Latin]
- Dozile (TN)
- Evanorm (TN)
- Mersyndol (TN)
- Restavit (TN)
- Somnil (TN)
- Syndol (TN)
- Unisom-2 (TN)
- Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether
- N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine
- N,N-dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine
- 2-(alpha-(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine
- 2-Dimethylaminoethoxyphenylmethyl-2-picoline
Reported adverse events
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