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CETIRIZINE
SynDRA canonical compound SYN0003060 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HRH1 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
| Indication | allergic rhinitis |
|---|
| Disease area | allergy |
|---|
All known targets
Mechanisms of action (all sources)
- Histamine receptor antagonist
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
- HRH1 INVERSE AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HRH2
- HTR2A
- HTR2B
- SLC6A4
- SLC6A3
- DRD2
- MC4R
- OPRD1
- NTSR1
- NR3C1
- NPY2R
- NPY1R
- MLNR
- KDR
- MC3R
- MAOA
- OPRM1
- KDM4A
- HTR3A
- HTR2C
- HTR1A
- HRH3
- OPRK1
- ACHE
- ORM1
- SLC22A2
- TBXA2R
- TACR1
- SLCO2B1
- SLCO1B3
- SLCO1B1
- SLC6A2
- SLC47A1
- SLC29A1
- SLC22A1
- HDAC6
- SCN5A
- SAMHD1
- PTGS2
- PTGS1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Histamine H1 Receptor Antagonists
- Histamine-1 Receptor Antagonist
- Anti-Allergic Agents
- Histamine Agents
- Histamine Antagonists
- Histamine H1 Antagonists
- Histamine H1 Antagonists, Non-Sedating
- Neurotransmitter Agents
ATC classes
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
- S01G · DECONGESTANTS AND ANTIALLERGICS
Cross-references
Synonyms
- Alleroff
- CETIRIZINE HYDROCHLORIDE
- CETIRIZINE HYDROCHLORIDE ALLERGY
- CETIRIZINE HYDROCHLORIDE AND PSEUDOEPHEDRINE HYDROCHLORIDE
- CETIRIZINE HYDROCHLORIDE HIVES
- CETIRIZINE HYDROCHLORIDE HIVES RELIEF
- CHILDREN'S CETIRIZINE HYDROCHLORIDE ALLERGY
- CHILDREN'S CETIRIZINE HYDROCHLORIDE HIVES RELIEF
- CHILDREN'S ZYRTEC ALLERGY
- CHILDREN'S ZYRTEC HIVES
- CHILDREN'S ZYRTEC HIVES RELIEF
- QUZYTTIR
- cetirizine hydrochloride
- cetirizine dihydrochloride
- cetirizine HCl
- Cetirizina
- Cetiderm
- AC-170
- 5-Bromo-2-hydroxymethylpyridine
- (5-Bromopyridin-2-yl)methanol
- 2-hydroxymethyl-5-bromopyridine
- 5-Bromo-2-(hydroxymethyl)pyridine
- (5-bromopyrid-2-yl)methanol
- 5-Bromo-2-pyridinemethanol
- (5-Bromo-pyridin-2-yl)-methanol
- 2-PYRIDINEMETHANOL, 5-BROMO-
- 5-BROMOPYRIDINE-2-METHANOL
- (5-bromo-2-pyridyl)methanol
- zlchem 391
- PubChem7710
- PubChem12387
- ACMC-209qrb
- AC1NP90H
- 5-bromo-2-pyridine methanol
- KSC494K9D
- Cetirizin
- Cetirizinum
- Cetryn
Reported adverse events
- Headache
- Nausea
- Pharyngitis
- Somnolence
- Abdominal pain
- Bronchospasm
- Vomiting
- Cough
- Epistaxis
- Hepatitis
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