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FLUOCINOLONE ACETONIDE
SynDRA canonical compound SYN0002977 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | NR3C1 | SERPINA6 |
|---|
| Mechanism of action | glucocorticoid receptor agonist |
|---|
| Indication | seborrheic dermatitis |
|---|
| Disease area | dermatology |
|---|
All known targets
- NR3C1
- PGR
- SERPINA6
- SMO
- ESRRA
- ESRRB
- ESRRG
Mechanisms of action (all sources)
- NR3C1 AGONIST
- NR3C1 MODULATOR
- Corticosteroid agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AR
- NPY2R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- ACHE
- KDR
- KDM4E
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- NPY1R
- OPRD1
- HIF1A
- SAMHD1
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SMAD3
- SLC6A4
- SLC6A3
- SLC6A2
- SIGMAR1
- PTPRC
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- KCMB2
- SYK
- PRGR
- NSD2
- NR1I2
- KSYK
- KCMB4
- KCMB1
- CFTR
- KCMA1
- IL1B
- GLI3
- ESRRA
- CP3A4
- CP2C9
- TLR3
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Inflammatory Agents
- Glucocorticoids
- Hormones
- Anti-Allergic Agents
ATC classes
- S01B · ANTIINFLAMMATORY AGENTS
- S02B · CORTICOSTEROIDS
- D07A · CORTICOSTEROIDS, PLAIN
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
- CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
- ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
- CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
Cross-references
Synonyms
- CAPEX
- Capex
- DERMA-SMOOTHE/FS
- DERMOTIC
- Dermotic
- FLAC
- FLUOCET
- FLUOCINONIDE ACETONIDE
- FLUONID
- FLUOTREX
- Flac
- fluocinolonacetonid
- fluocinolone acetonide dihydrate
- fluocinolone acetonide oil
- Fluocinolone
- Acetonide de fluocinolone
- Acetonido de fluocinolona
- Flucinolone acetonide
- Fluocinolide (acetate)
- Oto-synalar
- NSC-92339
- Derma-smoothe/fs
- Fluocet
- Fluocinolone acetonide component of iluvien
- Fluocinolone acetonide component of neo-synalar
- Fluocinolone acetonide component of otovel
- Fluocinolone acetonide component of tri-luma
- Fluonid
- Fluotrex
- Fs shampoo
- Synalar fte
- Synalar-c
- Synalar-hp
- Synalar-n
- Synandone
- Coriphate
Reported adverse events
- Milia
- Hypertrichosis
- Perioral dermatitis
- Dermatitis
- Headache
- Ear infection
- Folliculitis
- Nasopharyngitis
- Rash
- Telangiectasia
- Cushing's syndrome
- Skin atrophy
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