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MERIMEPODIB
SynDRA canonical compound SYN0002976 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | IMPDH1 |
|---|
| Mechanism of action | IMPDH inhibitor |
|---|
All known targets
- IMPDH1
- EGFR
- ERBB2
- IMPDH2
- Stap-coc blaZ
Mechanisms of action (all sources)
- IMPDH inhibitor
- IMPDH1 INHIBITOR
- Inosine-5'-monophosphate dehydrogenase 1 inhibitor
- IMPDH2 INHIBITOR
- inosine monophosphate dehydrogenase inhibitor
- Stap-coc blaZ INHIBITOR
- ERBB2 INHIBITOR
- EGFR INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- COMT
- CP2C9
- CP2D6
- CP3A7
- GAMT
- GNMT
- HNMT
- IFNG
- IP6K1
- KSYK
- NNMT
- NSD2
- PNMT
- SYK
Cross-references
Synonyms
- VI-21,497
- VI-21497
- VX-497
- Merimebodib
- Merimepodib [USAN:INN]
- Tyverb/Tykerb
- MMPD
- 2ZL2BA06FU
- C23H24N4O6
- CHEMBL304087
- MERIMEPODIB, VI-21497, VX-497
- UNII-2ZL2BA06FU
- Vx 497
- VX497
- Carbamic Acid
- Aminoformic acid
- UNII-O0UC6XOS4H
- O0UC6XOS4H
- CHEBI:28616
- OUT
- Carbamidsaeure
- Aminoformate
- ammoniocarboxylate
- Aminoameisensaeure
- imidocarbonic acid
- Aminomethanoic Acid
- aminocarboxylic acid
- AC1L18VM
- CHEMBL125278
- DTXSID5048009
- CTK1D6698
- 1111-78-0 (ammonium salt)
- KXDHJXZQYSOELW-UHFFFAOYSA-N
- 4366-93-2 (potassium salt)
- ZINC8383199
- BDBM50369454
- ABP000336
- Carbamic acid(6CI,7CI,8CI,9CI)
- ACM463774
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