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FENOFIBRIC ACID
SynDRA canonical compound SYN0002879 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CLCN1 | CYP2C19 | CYP2C8 | PPARA |
|---|
| Mechanism of action | cytochrome P450 inhibitor |
|---|
| Indication | dyslipidemia |
|---|
| Disease area | cardiology |
|---|
All known targets
- PPARA
- CLCN1
- CYP2C19
- CYP2C8
- FABP1
- FABP2
- Fabp1
- SLC22A12
- APOA1
- MMP25
- SLC6A2
- HTR2A
Mechanisms of action (all sources)
- PPARA AGONIST
- Peroxisome proliferator-activated receptor alpha agonist
- CLCN1 MODULATOR
- cytochrome P450 inhibitor
- FABP1 INHIBITOR
- PPAR receptor agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PPARG
- ACHE
- ADORA3
- TBXA2R
- SLC6A4
- SLC6A3
- SLC6A2
- PTGS1
- PPARD
- PGR
- PDE4A
- PDE3A
- OPRM1
- MAOA
- KDR
- KCNH2
- HTR2B
- HTR1A
- HRH3
- HDAC6
- F2
- ESR1
- DRD3
- DRD1
- CHRM2
- CHRM1
- AR
- ADRA2A
- ADRA1A
- TTR
Drug classes
- Anticholesteremic Agents
- Antimetabolites
- Hypolipidemic Agents
- Lipid Regulating Agents
- Peroxisome Proliferator Receptor alpha Agonist
- Peroxisome Proliferator-activated Receptor alpha Agonists
ATC classes
- C10A · LIPID MODIFYING AGENTS, PLAIN
- LIPID MODIFYING AGENTS, COMBINATIONS
Cross-references
Synonyms
- FIBRICOR
- Fibricor
- TRILIPIX
- Trilipix
- choline fenofibrate
- procetofenic acid
- Fenofibrate free acid
- Procetofenic acid
- LF-153
- NSC-281318
- Fenocor-67
- Lipanthyl
- Lofibra
- Supralip
- Fenofibrate related compound b
- 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid
- alpha 1081
- NSC 281318
- LF 178 acid
- UNII-BGF9MN2HU1
- 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid
- LF 153
- FNF Acid
- C17H15ClO4
- CCRIS 7302
- EINECS 255-626-9
- BGF9MN2HU1
- CHEMBL981
- BRN 2058973
- CHEBI:83469
- 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic Acid
- Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-
- AK117112
- W-106287
- fenofibrate related compound b
- fenofibric acid (usp-rs)
Reported adverse events
- Constipation
- Rhinitis
- Cholelithiasis
- Hypersensitivity
- Myopathy
- Pancreatitis
- Photosensitivity reaction
- Urticaria
- Headache
- Nausea
- Rhabdomyolysis
- Hepatotoxicity
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