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NIFLUMIC ACID
SynDRA canonical compound SYN0002835 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
| Indication | joint pain | muscle pain |
|---|
| Disease area | neurology/psychiatry | rheumatology |
|---|
All known targets
- CLCNKA
- PTGS2
- CLCNKB
- ANO1
- CLCN1
- KCNQ1
- KCNT2
- PTGS1
- DHODH
- GPR35
- PLA2G1B
- PLA2G4A
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- ANO1 INHIBITOR
- CLCN1 MODULATOR
- CLCNKA MODULATOR
- CLCNKB MODULATOR
- KCNT2 AGONIST
- KCNQ1 POSITIVE ALLOSTERIC MODULATOR
- PTGS2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- DRD2
- ACHE
- OPRM1
- OPRD1
- NR3C1
- NPY2R
- NPY1R
- NFKB1
- NFE2L2
- MPHOSPH8
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNK2
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- OPRK1
- PDE3A
- HRH2
- PDE4D
- VDR
- UGT1A8
- UGT1A1
- TEAD2
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- CP3A7
- ESRRA
- GPR32
- HDAC9
- NF2L2
- PHGDH
- PPARG
- RXRA
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- M02A · TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Cross-references
Synonyms
- niflamol
- nifluminic acid
- Acide niflumique
- Acido niflumico
- Niflugel
- NSC-758196
- UP-83
- Actol
- Donalgin
- Flunir
- Forenol
- Landruma
- NFL
- Niflactol
- Niflam
- Niflumate
- Nifluril
- Acide niflumique [French]
- Acido niflumico [Italian]
- Acidum niflumicum
- Nifluminic acid
- UPSA Conseil Brand of Niflumic Acid
- Upsamedica Brand of Niflumic Acid
- N 0630
- SC 1332
- UP 83
- UPSA Brand 1 of Niflumic Acid
- UPSA Brand 2 of Niflumic Acid
- Acid, Niflumic
- Acide niflumique [INN-French]
- Acido niflumico [INN-Spanish]
- Acidum niflumicum [INN-Latin]
- Niflugel (TN)
- Niflumic acid (INN)
- Niflumic acid [INN:DCF]
- Aza-2 dimethyl-2',3' (tetrazolyl-5)-6 diphenylamino
- Aza-2 dimethyl-2',3' (tetrazolyl-5)-6 diphenylamino [French]
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