← SynDRA

CLOROTEPINE

SynDRA canonical compound SYN0002832 — structure-anchored drug synonym record

All known targets

• ADRA1A
• DRD2
• HTR6
• HTR2C
• HRH1
• ADRA1B
• ADRA1D
• Drd5
• KCNK9
• Htr2c
• Htr2b
• Htr2a

Mechanisms of action (all sources)

• adrenergic receptor antagonist
• dopamine receptor antagonist
• HTR2C INHIBITOR
• HRH1 INHIBITOR
• ADRA1B INHIBITOR
• ADRA1D INHIBITOR
• DRD2 INHIBITOR
• ADRA1A INHIBITOR
• HTR6 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ARSA
• ATAD5
• USP1
• UBE2N
• TRPV1
• TDP1
• RAD52
• RAB9A
• POLK
• PMP22
• NPC1
• MTOR
• MPHOSPH8
• MAPT
• LMNA
• KDM4A
• KCNH2
• GMNN
• GLP1R
• GBA1
• EHMT2
• CBX1
• ATXN2
• VDR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• 5HT2A
• GLI3
• RARA
• PRGR
• PPARG
• PNMT
• NNMT
• KSYK
• JUN
• IFNG
• HNMT
• GNMT
• GAMT
• ACM1
• ESRRA
• CP3A7
• CP3A4
• CP2D6
• CP2CJ
• CP2C9
• COMT
• CASP7
• CASP3
• ANDR
• SYK

Cross-references

• PubChem CID: 1238
• ChEMBL: CHEMBL64249
• DrugBank: DB15971
• ChEBI: CHEBI:135459
• Wikipedia: Clorotepine
• TTD: D0D3YN

Synonyms

• (+/-)-Clothepin
• octoclothepin
• chlorothepin
• clotepin
• clothepin
• octoclothepine
• Clorotepina
• Clothepin
• OCTOCLOTHEPIN
• Octoclothepine
• Clotepin
• Clorotepine [INN]
• Clorotepinum [INN-Latin]
• Clorotepina [INN-Spanish]
• CHEMBL64249
• 1-(8-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-methylpiperazine
• Piperazine, 1-(8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-methyl-
• clothepine
• clorothepin
• Clorotepinum
• 1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine
• VUFB-6281
• Octoclothepin maleate
• CLOROTEPINE(-)
• AC1Q3SXZ
• CLOROTEPINE (+)
• OCTOCLOTHEPIN,(-)
• RefChem:928121
• Octoclothepin
• E65W20MU7A
• Clotepin; Clothepin; Octoclothepin; OctoclothepineV
• UNII-E65W20MU7A
• (+/-)-Octoclothepin
• OCTOCLOTHEPIN,(+)
• Lopac0_000885
• CLOROTEPINE [WHO-DD]
• SCHEMBL678917
• SCHEMBL29822559