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TEMAZEPAM
SynDRA canonical compound SYN0002815 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | GABRQ |
|---|
| Mechanism of action | GABA receptor agonist |
|---|
All known targets
- GABRA1
- GABRG2
- GABRB2
- GABRA2
- GABRQ
- GABRP
- GABRG3
- GABRG1
- GABRE
- GABRD
- GABRB3
- GABRB1
Mechanisms of action (all sources)
- GABA receptor agonist
- GABRA1 POSITIVE ALLOSTERIC MODULATOR
- GABRB2 POSITIVE ALLOSTERIC MODULATOR
- GABRG2 POSITIVE ALLOSTERIC MODULATOR
- GABRB3 POSITIVE ALLOSTERIC MODULATOR
- GABRA4 POSITIVE ALLOSTERIC MODULATOR
- GABRG3 POSITIVE ALLOSTERIC MODULATOR
- GABRQ POSITIVE ALLOSTERIC MODULATOR
- GABRA3 POSITIVE ALLOSTERIC MODULATOR
- GABRP POSITIVE ALLOSTERIC MODULATOR
- GABRD POSITIVE ALLOSTERIC MODULATOR
- GABRG1 POSITIVE ALLOSTERIC MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- OPRK1
- PDE3A
- ESR1
- ADRB2
- MC3R
- NTSR1
- NR3C1
- NPY2R
- NPY1R
- MLNR
- MC4R
- ADORA1
- OPRD1
- LMNA
- KCNH2
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- MAOA
- OPRM1
- HRH3
- PDE4D
- PGR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TACR1
- TBXA2R
- UGT1A1
- UGT1A6
- UGT1A9
- UGT2B10
- UGT2B4
- HTR1A
- HRH1
- HRH2
- AGTR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP1A2
- CP2C9
- CP2CJ
- GCR
- GLI3
- NR1I2
- RARA
Drug classes
- Anti-Anxiety Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- GABA Agents
- GABA Modulators
- Hypnotics and Sedatives
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
- Benzodiazepine
ATC classes
- N05C · HYPNOTICS AND SEDATIVES
- N05B · ANXIOLYTICS
Cross-references
Synonyms
- RESTORIL
- Restoril
- TEMAZ
- (RS)-Temazepam
- levanxene
- levanxol
- (rs)-temazepam
- NSC-246303
- WY-3917
- Kentepam
- Normison
- Temaz
- Temazepam civ
- Cerepax
- Crisonar
- Dasuen
- Euhypnos
- Euipnos
- Gelthix
- Hydroxydiazepam
- Lenal
- Levanxene
- Levanxol
- Levanzene
- Mabertin
- Methyloxazepam
- Nocturne
- Nomapam
- Normitab
- Nortem
- Oxydiazepam
- Perdorm
- Planum
- Remestan
- Signopam
- Temador
- Temaze
Reported adverse events
- Anxiety
- Depression
- Vertigo
- Amnesia
- Dizziness
- Fatigue
- Hangover
- Headache
- Lethargy
- Nausea
- Nervousness
- Nightmare
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