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SUPROFEN
SynDRA canonical compound SYN0002773 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- PTGS2 INHIBITOR
- PTGS1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- HTR1A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- KDM4E
- MAOA
- MC3R
- MC4R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- RXFP1
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- TBXA2R
- HTR2A
- HRH3
- ADORA2A
- HRH2
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Cross-references
Synonyms
- PROFENAL
- masterfen
- (+/-)-Suprofen
- profenol
- racemic suprofen
- sutoprofen
- suprofen RS
- Suprofene
- Suprofeno
- P-(2-thenoyl)hydratropic acid
- P-2-thenoylhydratropic acid
- Racemic suprofen
- Srendam
- Sulproltin
- Sutoprofen
- Topalgic
- NSC-303611
- R-25,061
- R-25061
- TN-762
- Profenal
- Maldocil
- Masterfen
- Suprocil
- Suprofenum
- Suprol
- R25061
- TN762
- Profenal (TN)
- Suprofene [INN-French]
- Suprofenum [INN-Latin]
- TYN-762P
- P-2-Thenoylhydratropic acid
- Suprofen (JAN/USP/INN)
- Suprofen [USAN:BAN:INN:JAN]
- Alpha-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid
- (+-)-2-(p-(2-Thenoyl)phenyl)propionic acid
- (-)-alpha-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid
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