← SynDRA
(-)-U-50488
SynDRA canonical compound SYN0002766 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | OPRK1 |
|---|
| Mechanism of action | opioid receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SIGMAR1
- ALDH1A1
- KAT2A
- TSHR
- TP53
- TDP1
- RGS4
- RAB9A
- OPRM1
- OPRD1
- MTOR
- HDAC6
- ALOX15B
- EHMT2
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- CBX1
- ATXN2
- ARSA
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- B2CL1
- COMT
- CP1A2
- CP2CJ
- CP2D6
- CP3A4
- GAMT
- GNMT
- HNMT
- ID4
- KCNH2
- MCL1
- NNMT
- PNMT
Cross-references
Synonyms
- BRD-K53532120
- U-50488-(-)
- (-)-U 50488
- (+/-) trans-U-50488 methanesulfonate
- Tocris-0471
- Tocris-0495
- Tocris-0496
- Lopac0_000472
- Lopac0_001266
- BSPBio_001511
- KBioGR_000231
- KBioSS_000231
- SCHEMBL10804846
- SCHEMBL31048809
- KBio2_000231
- KBio2_002799
- KBio2_005367
- KBio3_000461
- KBio3_000462
- CHEBI:107647
- Bio1_000413
- Bio1_000902
- Bio1_001391
- Bio2_000231
- Bio2_000711
- HMS1361L13
- HMS1791L13
- HMS1989L13
- HMS3402L13
- BDBM50000780
- CCG-204564
- SDCCGSBI-0050457.P004
- IDI1_033981
- NCGC00024605-01
- NCGC00024605-02
- NCGC00024605-03
- NCGC00024605-04
- NCGC00024605-05
- NCGC00024605-06
Look up (-)-U-50488 in the interactive SynDRA portal →