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T091317
SynDRA canonical compound SYN0002765 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | NR1H2 |
|---|
| Mechanism of action | ABC transporter expression enhancer |
|---|
All known targets
- NR1H2
- NR1H3
- RORA
- RORC
- ABCA1
- NCOA1
- NCOA2
- NR1I2
- RXRB
Mechanisms of action (all sources)
- LXR agonist
- ROR inverse agonist
- ABC transporter expression enhancer
- NR1H3 AGONIST
- NR1H2 AGONIST
- RORA INVERSE AGONIST
- RORC INVERSE AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- RORB
- SREBF1
- HNF4A
- NR1I3
- NR1H4
- RXRA
- ALDH1A1
- POLK
- PPARA
- PPARD
- PPARG
- PTH1R
- RAPGEF3
- RAPGEF4
- SAMHD1
- OGG1
- SMAD3
- SMUG1
- SNCA
- TARDBP
- TDG
- TDP1
- THRB
- UNG
- POLI
- NR5A1
- NTHL1
- MBD4
- ATXN2
- DHODH
- ESR1
- GLP1R
- GSK3B
- HDAC6
- IDH1
- MAPT
- MUTYH
- AR
- NEIL2
- NFE2L2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADA10
- ADA17
- RARG
- RARB
- RARA
- PSENEN
- PSEN2
- PSEN1
- PRIO
- PLCG1
- NSD2
- NR4A2
- NF2L2
- NCSTN
- KSYK
- IFNG
- HNF4G
- GCR
- G6PC1
- ERR3
- CSTA
- COT1
- APH1B
- APH1A
- ANDR
- SYK
Cross-references
Synonyms
- ML125
- T-0901317
- T0901317
- TO-901317
- TO901317
- UNII-A07663A39I
- CHEMBL62136
- N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
- A07663A39I
- N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE
- N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide
- T-1317
- TO 901317
- T 0901317
- T 1317
- J1.503.100J
- T1371 cpd
- RefChem:926602
- T-1371
- MFCD03412028
- C17H12F9NO3S
- [3H]T0901317
- SR-05000000453
- 1pqc
- 2o9i
- 4nb6
- MLS002554297
- SCHEMBL457231
- GTPL2755
- orb1300551
- BDBM19993
- GLXC-02675
- HMS3268P10
- HMS3413I08
- HMS3649G14
- HMS3652B22
- HMS3677I08
- HMS3886B11
- EX-A1278
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