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LACOSAMIDE
SynDRA canonical compound SYN0002703 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SCN10A |
|---|
| Mechanism of action | Collapsin response mediator protein stimulant |
|---|
All known targets
- SCN9A
- SCN10A
- SCN3A
- SCN1A
- SCN11A
- DPYSL2
- SCN8A
- SCN7A
- SCN5A
- SCN4A
- SCN2A
- Scn2a
Mechanisms of action (all sources)
- Sodium channel blocker
- Collapsin response mediator protein inhibitor
- Collapsin response mediator protein stimulant
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CACNA1C
- HDAC6
- KCND3
- KCNH2
Drug classes
- Anticonvulsants
- Cardiovascular Agents
- Central Nervous System Agents
- Membrane Transport Modulators
- Sodium Channel Blockers
- Voltage-Gated Sodium Channel Blockers
ATC classes
Cross-references
Synonyms
- MOTPOLY XR
- Motpoly
- VIMPAT
- Vimpat
- ertosamide
- SPM-927
- erlosamide
- harkoseride
- vimpat
- Erlosamide
- Lacosamida
- (r)-lacosamide 1
- ADD-243037
- ADD243037
- SPM927
- Lacosamide accord
- Lacosamide adroiq
- Lacosamide ucb
- Motpoly xr
- Lacosamide cv
- Harkoseride
- Erlosamide [INN]
- Lacosamide [USAN]
- ADD-234037
- SPM-929
- Erlosamide, Vimpat, Lacosamide
- Lacosamide (USAN/INN)
- (2R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide
- lacosamide (ep monograph)
- MOTPOLY
- lacosamide (usp monograph)
- (2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide
- (+)-(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide
- lacosamide (usp-rs)
- ADD 243037
- DTXCID2031455
- lacosamidum
Reported adverse events
- Aggression
- Asthenia
- Depression
- Diplopia
- Fatigue
- Nausea
- Nystagmus
- Pruritus
- Syncope
- Tremor
- Vertigo
- Vomiting
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