← SynDRA

DIPHENIDOL

SynDRA canonical compound SYN0002672 — structure-anchored drug synonym record

All known targets

• CHRM1
• CHRM4
• CHRM3
• CHRM2
• Adra1b
• CHRM5
• CYP2D6
• DRD2
• DRD3
• HTR2A
• SCN1A
• SCN2A

Mechanisms of action (all sources)

• Acetylcholine receptor agonist
• CHRM1 ANTAGONIST
• Muscarinic acetylcholine receptor M1 antagonist
• TAS2R13 AGONIST
• TAS2R20 AGONIST
• CHRM4 ANTAGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• DRD1
• HTR1A
• ACHE
• MMP9
• MMP1
• MC5R
• MC4R
• MC3R
• MAPK3
• MAPK14
• MAPK1
• MAOA
• LMNA
• NPY2R
• LCK
• KDR
• KDM4E
• KCNH2
• HTR6
• HTR2C
• HTR2B
• HRH3
• HRH2
• NPY1R
• NR3C1
• HMGCR
• OPRD1
• TDP1
• TBXAS1
• TBXA2R
• TACR2
• TACR1
• SLC6A4
• SLC6A3
• SLC6A2
• SAMHD1
• PTPRC
• PTGS2
• PTGS1
• PTAFR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ACM4
• CP2D6
• MDR1

Drug classes

• Antiemetics
• Central Nervous System Agents
• Gastrointestinal Agents
• Peripheral Nervous System Agents
• Antiemetic

Cross-references

• PubChem CID: 3055
• ChEMBL: CHEMBL936
• DrugBank: DB01231
• ChEBI: CHEBI:4638
• KEGG: D01318
• RxNorm: 23370
• Wikipedia: Diphenidol
• TTD: D0W9VB
• LINCS BRD: BRD-K01663662

Synonyms

• VONTROL
• cephadol
• difenidol
• diphenadol
• lansenol
• diphenidol hydrochloride
• difenidol hydrochloride
• difenidol embonate
• diphenidol HCl
• difenidol HCl
• Difenidol
• Difenidol hydrochloride
• SK&F-478
• SK-478
• Vontrol
• Avomol
• Defenidol
• Difenidolo
• Difenidolum
• Nometic
• Difenidol HCl
• Difenidolo [DCIT]
• SKF 478
• Difenidolum [INN-Latin]
• Diphenidol [USAN:BAN]
• Diphenidol (USAN/INN)
• Alpha,alpha-Diphenyl-1-piperidinebutanol
• Diphenyl(3-(1-piperidyl)propyl)carbinol
• alpha,alpha-Diphenyl-1-piperidinebutanol
• NQO8R319LY
• CHEBI:4638
• Benzhydrol, alpha-(3-piperidinopropyl)-
• 1-Piperidinebutanol, alpha,alpha-diphenyl-
• DTXCID502950
• RefChem:588811
• SK&F 478-J
• Diphenidol [USAN]
• Difenidol [INN]