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DOBUTAMINE
SynDRA canonical compound SYN0002610 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ADRB2 |
|---|
| Mechanism of action | Adrenergic receptor agonist |
|---|
| Indication | congestive heart failure |
|---|
| Disease area | cardiology |
|---|
All known targets
- ADRB1
- ADRB2
- ADRA1A
- FYN
- CA9
- COMT
- Ca15
- DRD3
- EGFR
- Pgrmc1
- LCK
- CA6
Mechanisms of action (all sources)
- Adrenergic receptor agonist
- ADRB1 AGONIST
- Beta-1 adrenergic receptor agonist
- ADRB2 AGONIST
- Beta-2 adrenergic receptor agonist
- ADRB1 PARTIAL AGONIST
- matrix metalloprotease inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PTGS2
- HTR2A
- OPRK1
- OPRM1
- ADRA2C
- DRD4
- DRD2
- KCNH2
- DRD1
- MLNR
- MC4R
- MC5R
- ABCB11
- MMP1
- MC3R
- MPHOSPH8
- NPY1R
- NPY2R
- MMP9
- MAPT
- NR1I2
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- KDM4E
- IDH1
- HTT
- HTR6
- HTR3A
- HTR2C
- HTR2B
- NR1H4
- OPRD1
- NR3C1
- NTSR1
- TTR
- TDP1
- TBXAS1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALOX12
- ALR
- CP2D6
- CP3A7
- HS90A
- HS90B
- LOX12
- SC5A7
Drug classes
- Adrenergic beta-Agonists
- beta-Adrenergic Agonist
- Adrenergic Agents
- Adrenergic Agonists
- Adrenergic beta-1 Receptor Agonists
- Cardiotonic Agents
- Cardiovascular Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Protective Agents
- Sympathomimetics
ATC classes
- C01C · CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
Cross-references
Synonyms
- DOBUTAMINE HYDROCHLORIDE
- DOBUTAMINE HYDROCHLORIDE IN DEXTROSE 5%
- DOBUTAMINE HYDROCHLORIDE IN DEXTROSE 5% IN PLASTIC CONTAINER
- DOBUTREX
- dobutamine hydrochloride
- dobutamine HCl
- Dobutamina
- Dl-dobutamine
- Racemic dobutamine
- COMPOUND-81929
- Dobutaminum
- Dobutamine Hcl
- Dobutamine [USAN]
- Dobutamine hydrobromide
- LY 81929
- Lilly 81929
- DL-dobutamine
- Dobutamina [INN-Spanish]
- Dobutamine Hcl in Dextrose 5%
- Dobutamine(usp)
- Dobutaminum [INN-Latin]
- Rac-dobutamine
- Racemic-Dobutamine
- Dobutamine (USP/INN)
- Dobutamine [USAN:BAN:INN]
- (+-)-4-(2-((3-(p-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
- (+-)-dobutamine
- 3S12J47372
- dobutamine (usp impurity)
- rac-dobutamine
- CHEBI:4670
- DTXCID702958
- Dobutamin ratiopharm
- Tartrate, Dobutamine
- Hydrobromide, Dobutamine
- Lactobionate, Dobutamine
- RefChem:56520
- C01CA07
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