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RISEDRONIC ACID
SynDRA canonical compound SYN0002578 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | FDPS |
| Mechanism of action | Osteoclast inhibitor |
| Indication | osteoporosis | Paget's disease |
| Disease area | endocrinology | orthopedics |
All known targets
Mechanisms of action (all sources)
- Osteoclast inhibitor
- FDPS INHIBITOR
- Farnesyl diphosphate synthase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PDE3A
- ACHE
- MMP9
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KCNH2
- HTR7
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GIPR
- GHSR
- GGPS1
- GCGR
- MMP1
- NPY1R
- ACMSD
- PTGS2
- TTR
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
Drug classes
- Bisphosphonate
- Bone Density Conservation Agents
- Calcium Channel Blockers
- Calcium-Regulating Hormones and Agents
- Cardiovascular Agents
- Membrane Transport Modulators
ATC classes
- M05B · DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
Cross-references
Synonyms
- ACTONEL
- ACTONEL WITH CALCIUM (COPACKAGED)
- ATELVIA
- Actonel
- RISEDRONATE SODIUM
- risedronate sodium hemi-pentahydrate
- risedronate sodium monohydrate
- risedronate sodium anhydrous
- risedronate sodium hydrate
- sodium risedronate
- sodium risedronate hydrate
- risedronate
- risedronate sodium
- actonel
- risedronic acid monosodium salt
- risedronic acid monohydrate
- Acide risedronique
- Acido risedronico
- Ridron
- Risedronate
- M05BA07
- Atelvia
- Acidum risedronicum
- Benet
- Risedronic acid [INN:BAN]
- Acidum risedronicum [INN-Latin]
- Acido risedronico [INN-Spanish]
- Acide risedronique [INN-French]
- Risedronic acid monohydrate
- NE-58095
- UNII-KM2Z91756Z
- C7H11NO7P2
- NE 58019
- HSDB 7326
- [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid
- Risedronic acid (Actonel)
- CHEMBL923
- CHEBI:8869
Reported adverse events
- Arthralgia
- Back pain
- Constipation
- Duodenitis
- Dyspepsia
- Headache
- Hypersensitivity
- Nausea
- Osteonecrosis
- Asthenia
- Rash
- Abdominal pain upper
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