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CHOLINE
SynDRA canonical compound SYN0002568 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ACHE | BCHE | CHRNA2 | PCYT1A | PCYT1B | PHOSPHO1 | PLD1 | PLD2 |
|---|
| Mechanism of action | acetylcholine precursor |
|---|
All known targets
- ACHE
- CHRNA2
- PCYT1B
- PDE1B
- PDE3A
- PDE3B
- PDE4A
- PDE4B
- PDE4C
- PDE4D
- PHOSPHO1
- PIK3CD
Mechanisms of action (all sources)
- acetylcholine precursor
- CHRNA2 INHIBITOR
- ACHE INHIBITOR
- SOD1 INHIBITOR
- ADORA2A ANTAGONIST
- ADORA1 ANTAGONIST
- ADORA2B ANTAGONIST
- PDE3B INHIBITOR
- PDE3A INHIBITOR
- PDE4A INHIBITOR
- PDE4B INHIBITOR
- PDE4C INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- KCNH2
- ADRA1A
- MAPK14
- OPRD1
- NR3C1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK1
- HRH1
- MAOA
- LMNA
- LCK
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- OPRK1
- OPRM1
- PDE5A
- SLC47A1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC47A2
- SLC22A5
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- ANDR
- CP1A2
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- ESRRA
- GLI3
- NR1I2
- PRGR
- RARA
Drug classes
- Antimetabolites
- Central Nervous System Agents
- Gastrointestinal Agents
- Hypolipidemic Agents
- Lipid Regulating Agents
- Lipotropic Agents
- Nootropic Agents
- Cholagogues and Choleretics
- Anti-Asthmatic Agents
- Bronchodilator Agents
- Cardiovascular Agents
- Enzyme Inhibitors
ATC classes
- OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
- PARASYMPATHOMIMETICS
Cross-references
Synonyms
- CHOLEDYL
- CHOLEDYL SA
- OXTRIPHYLLINE
- OXTRIPHYLLINE PEDIATRIC
- VYKAT XR
- Vykat
- choline chloride
- vitamin J
- bilineurine
- choline ion
- choline bitartrate
- choline dehydrocholate
- biscolan
- choline theophyllinate
- cholinophylline
- theophylline cholinate
- oxtriphylline
- Choline ion
- Bilineurine
- Choline cation
- Cholinum
- 2-Hydroxy-N,N,N-trimethylethanaminium
- (2-Hydroxyethyl)trimethylammonium
- trimethylethanolamine
- N-trimethylethanolamine
- Ethanaminium, 2-hydroxy-N,N,N-trimethyl-
- CCRIS 5847
- UNII-N91BDP6H0X
- AI3-24208
- BRN 1736748
- N,N,N-trimethylethanol-ammonium
- CHEBI:15354
- (beta-hydroxyethyl)trimethylammonium
- EINECS 200-535-1
- CHEMBL920
- N91BDP6H0X
- 2-hydroxyethyl(trimethyl)ammonium
- Oxtriphylline
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