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FLOXURIDINE

SynDRA canonical compound SYN0002561 — structure-anchored drug synonym record

All known targets

• TYMS
• Candi TMP1
• Tyms

Mechanisms of action (all sources)

• TYMS INHIBITOR
• thymidylate synthase inhibitor
• DNA synthesis inhibitor
• Candi TMP1 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ABCC5
• MAPK1
• OPRD1
• NR3C1
• NPY2R
• NPY1R
• NFE2L2
• MMP9
• MMP1
• MC5R
• MC4R
• MC3R
• MAPK3
• MAPK14
• MAOB
• ACHE
• MAOA
• LMNA
• LCK
• KDR
• KCNH2
• IDH1
• HTR6
• HTR2C
• HTR2B
• HTR2A
• HTR1A
• HRH3
• OPRK1
• OPRM1
• PDE3A
• PDE4A
• TYMP
• TDP1
• TBXAS1
• TBXA2R
• TACR2
• TACR1
• SMN1
• SLCO1B3

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• A4
• ATXN2
• TF65
• SYK
• PARP1
• NSD2
• NFKB1
• NF2L2
• NCOA3
• NCOA1
• MMP14
• KSYK
• KLF5
• JAK2
• IFNG
• IDHC
• ESRRA
• TP53

Drug classes

• Antimetabolites
• Antimetabolites, Antineoplastic
• Antineoplastic Agents
• Noxae
• Antimetabolite

ATC classes

• L01B · ANTIMETABOLITES

Cross-references

• PubChem CID: 5790
• ChEMBL: CHEMBL917
• DrugBank: DB00322
• ChEBI: CHEBI:60761
• KEGG: D04197
• RxNorm: 4488
• Wikipedia: Floxuridine
• TTD: D0TS1Z
• LINCS BRD: BRD-K47832606

Synonyms

• FUDR
• floxuridin
• 5-Fluorouracil deoxyriboside
• 5-Fluorodeoxyuridine
• Floxuridina
• 5-fluoro-2-deoxyuridine
• 5-fudr
• Fluoruridine deoxyribose
• Fudr
• NSC-27640
• F.u.d.r.
• 2'-Deoxy-5-fluorouridine
• 5 Fluorodeoxyuridine
• Fluorodeoxyuridine
• Floxuridin
• Deoxyfluorouridine
• 5-Fluoro-2'-deoxyuridine
• FdUrd
• Floxuridinum
• Floxiridina
• 5FdU
• 5-Fluoro-2-desoxyuridine
• Floxuridinum [INN-Latin]
• FDUR
• Floxiridina [INN-Spanish]
• beta-5-Fluoro-2'-deoxyuridine
• 5-Fluoro-2-deoxyuridine
• 5-FdUrd
• Sterile fudr (TN)
• Floxuridine/5-fluorouracil
• 5-Fluorouracil 2'-deoxyriboside
• 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil
• Uridine, 2'-deoxy-5-fluoro
• NSC 27640
• 1beta-D-2'-Deoxyribofuranosyl-5-flurouracil
• 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil
• 5-FUDR