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DANTHRON

SynDRA canonical compound SYN0002559 — structure-anchored drug synonym record

All known targets

• RXRA
• MAOA
• MAOB

Mechanisms of action (all sources)

• RXRA ANTAGONIST
• Retinoid X receptor alpha antagonist

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ALDH1A1
• THRB
• PPARG
• RORC
• SAMHD1
• SIRT3
• SMN1
• TDP1
• TSHR
• ALOX15
• TTR
• UGT1A1
• UGT1A10
• UGT1A6
• UGT1A7
• UGT1A9
• PPARD
• NFE2L2
• MBNL1
• MAPT
• MAPK1
• LMNA
• KAT2A
• HTT
• HSD17B10
• HPGD
• HDAC6
• ESR1
• EHMT2
• CXCL8
• CSNK2A1
• BAZ2B
• APEX1
• VDR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ANDR
• B2CL1
• CASP1
• CP1A2
• CP2CJ
• CP3A7
• ESRRA
• MCL1
• NF2L2
• NLRP1
• PHGDH
• TP53

Drug classes

• Cathartics
• Gastrointestinal Agents
• Mutagens
• Noxae
• laxative

ATC classes

• A06A · DRUGS FOR CONSTIPATION

Cross-references

• PubChem CID: 2950
• ChEMBL: CHEMBL53418
• DrugBank: DB04816
• ChEBI: CHEBI:3682
• KEGG: D07107
• RxNorm: 22293
• PDB: CHZ
• Wikipedia: Dantron
• TTD: D0J0EL
• LINCS BRD: BRD-K10065684

Synonyms

• dantron
• antrapurol
• chrysazin
• danthrone
• diaquone
• dionone
• laxanorm
• laxanthreen
• 1,8-Dihydroxyanthraquinone
• Dantron
• Dantrone
• Pilules vinchy n.f.
• NSC-38626
• NSC-646568
• Dorbane
• Istizin
• 1,8-dihydroxy-anthraquinone
• Chrysazin
• Antrapurol
• 1,8-Dihydroxyanthracene-9,10-dione
• Diaquone
• Altan
• Laxanorm
• Laxanthreen
• Laxipurin
• Dionone
• Zwitsalax
• Danivac
• 9,10-Anthracenedione, 1,8-dihydroxy-
• 1,8-Dihydroxy-9,10-anthraquinone
• Dioxyanthrachinonum
• Usaf nd-59
• 1,8-Dihydroxyanthrachinon
• 1,8-Dihydroxy-9,10-anthracenedione
• Dantrona
• Dantronum
• LTAN
• 1,8-Dihydroxyanthra-9,10-quinone