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ISOXICAM
SynDRA canonical compound SYN0002476 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Primary target(s) | PTGS1 | PTGS2 |
|---|
| Mechanism of action | cyclooxygenase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- PTGS2 INHIBITOR
- Cyclooxygenase inhibitor
- PTGS1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- ADORA3
- HTR2B
- KCNH2
- KDR
- LMNA
- MAOA
- OPRM1
- PDE3A
- PDE4A
- PGR
- POLI
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- TBXA2R
- TDP1
- HTR1A
- HRH3
- HDAC6
- CYP1A2
- ADRA1A
- ADRA2A
- ALB
- AR
- CBX1
- CHRM1
- CHRM2
- CYP2C19
- F2
- CYP2C9
- CYP2D6
- CYP3A4
- DRD1
- DRD3
- EHMT2
- ESR1
- USP2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Peripheral Nervous System Agents
- Sensory System Agents
Cross-references
Synonyms
- floxicam
- vectren
- W 8495
- NSC-758436
- W-8495
- Maxicam
- Isoxicamo
- Isoxicamum
- UNII-8XU734C4NG
- Pacyl (antiinflammatory)
- Isoxicamum [INN-Latin]
- Isoxicamo [INN-Spanish]
- EINECS 252-084-5
- BRN 0577221
- 8XU734C4NG
- CHEBI:76163
- C14H13N3O5S
- NCGC00016829-05
- CAS-34552-84-6
- 4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
- DSSTox_CID_25462
- DSSTox_RID_80893
- DSSTox_GSID_45462
- NSC 758436
- DTXCID8025462
- RefChem:792457
- SR-01000003112
- Isoxicam [USAN:INN:BAN]
- Prestwick_505
- Maxicam (TN)
- Isoxicam (Standard)
- Spectrum_001605
- ISOXICAM [USAN]
- Isoxicam (USAN/INN)
- ISOXICAM [INN]
- ISOXICAM [MI]
- Prestwick0_000044
- Prestwick1_000044
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