← SynDRA
FAMOTIDINE
SynDRA canonical compound SYN0002474 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HRH2 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
| Indication | heartburn |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- HRH2
- CA1
- CA12
- SLC47A2
- SLC47A1
- SLC22A3
- SLC22A2
- HSP90AA1
- CA9
- CA7
- CA6
- CA5B
Mechanisms of action (all sources)
- Histamine receptor antagonist
- HRH2 ANTAGONIST
- Histamine H2 receptor antagonist
- TAS2R31 AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- MAOA
- ACHE
- MC3R
- MC5R
- MLNR
- MMP1
- MMP9
- MPG
- MUTYH
- NEIL1
- NEIL2
- NPY1R
- NPY2R
- NR3C1
- NTHL1
- NTSR1
- OGG1
- OPRD1
- OPRK1
- MC4R
- MBD4
- ADGRF1
- MAPK3
- HRH3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- HTR5A
- HTR6
- HTR7
- KCNH2
- KDM4A
- LCK
- LMNA
- MAPK1
- MAPK14
- OPRM1
- PDE3A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Histamine H2 Receptor Antagonists
- Histamine-2 Receptor Antagonist
- Anti-Ulcer Agents
- Gastrointestinal Agents
- Histamine Agents
- Histamine Antagonists
- Histamine H2 Antagonists
- Neurotransmitter Agents
ATC classes
- A02B · DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Cross-references
Synonyms
- DUEXIS
- FAMOTIDINE PRESERVATIVE FREE
- FAMOTIDINE PRESERVATIVE FREE (PHARMACY BULK)
- FAMOTIDINE PRESERVATIVE FREE IN PLASTIC CONTAINER
- FAMOTIDINE, CALCIUM CARBONATE, AND MAGNESIUM HYDROXIDE
- FLUXID
- IBUPROFEN AND FAMOTIDINE
- PEPCID
- PEPCID AC
- PEPCID COMPLETE
- PEPCID PRESERVATIVE FREE
- agufam
- amfamox
- antodine
- apogastine
- bestidine
- brolin
- cepal
- digervin
- dispromil
- Famotidina
- Amfamox
- Fadul
- Famodil
- Famosan
- Famoxal
- Ganor
- Gastridin
- Gastropen
- Lecedil
- Motiax
- Muclox
- Pepcidac
- Pepdine
- Pepdul
- L 643341
- MK-208
Reported adverse events
- Bleeding
- GI bleed
- Perforation
- Ulceration
- Elderly
- Hypersensitivity
- Stevens-Johnson syndrome
- Headache
- Constipation
- Nausea
- Cough
- Vomiting
Look up FAMOTIDINE in the interactive SynDRA portal →