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GOSSYPOL
SynDRA canonical compound SYN0002472 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | BCL2L1 |
|---|
| Mechanism of action | MCL1 inhibitor |
|---|
All known targets
- BCL2
- BCL2L1
- MCL1
- BCL2L2
- AKR1B1
- LDHB
- ampC
- SLC2A1
- MPG
- MDH2
- MDH1
- LDH
Mechanisms of action (all sources)
- BCL inhibitor
- MCL1 INHIBITOR
- BCL2 REGULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- RAD52
- VCP
- AR
- SLCO1B1
- SLCO1B3
- NR1H4
- POLK
- POLI
- POLB
- PKM
- PIN1
- NR3C1
- NPSR1
- PPARD
- NPC1
- NFKB1
- NFE2L2
- MTOR
- MPHOSPH8
- MDM2
- MBNL1
- PPARA
- ALB
- PPARG
- RAB9A
- VDR
- USP2
- USP1
- TST
- TP53
- THRB
- TDP1
- SNCA
- SMN1
- SMAD3
- SAMHD1
- RXRA
- RGS4
- RECQL
- MAPK1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- PAX8
- PRGR
- PPM1D
- PNMT
- PLIN5
- PLIN1
- PHGDH
- PE2R2
- PABP1
- PSIP1
- NTMT1
- NTM1A
- NSD2
- NNMT
- MPI
- MK01
- MDR1
- PRMT1
- RAPGEF3
- ABL1
- STK33
- UBP1
- UBA2
- TSHR
- THB
- TERA
- SYK
- SUMO1
- SIRT5
- RIN1
- SIAE
- SENP8
- SAE1
- S1PR4
- S12A5
- RXFP1
- RPGF3
- M4K2
- M3K3
Drug classes
- Contraceptive Agents
- Contraceptive Agents, Male
- Reproductive Control Agents
- Antineoplastic Agents, Phytogenic
- Contraceptive Agents, Female
- Spermatocidal Agents
Cross-references
Synonyms
- gossypol sodium
- gossypol dipotassium
- gossypol potassium
- gosipol
- (-)-gossypol
- No fertil
- Pogosin
- Tash 1
- BL-193
- NSC-56817
- NSC-624336
- (-)-Gossypol
- (+)-Gossypol
- racemic-Gossypol
- (R)-(-)-Gossypol
- (R)-Gossypol
- (+-)-Gossypol
- (+/-)-Gossypol
- CCRIS 2689
- NSC56817
- NSC 56817
- NSC 624336
- BRN 1917878
- CHEMBL51483
- AI3-22957
- 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-8,8'-dicarbaldehyde
- 2,2'-bi[8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene]
- 2,2'-Bis(1,6,7-trihydroxy-3-methyl-5-isopropyl-8-aldehydonaphthalene)
- NSC624336
- Gossypol acetate
- No Fertil
- AT 101
- 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
- AT101
- Gossypol, (R)-
- Gossypol, (S)-
- XNA7DR63CQ
- 8DY2X8LXW4
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