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KENPAULLONE
SynDRA canonical compound SYN0002459 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CDK1 |
|---|
| Mechanism of action | GSK-3 inhibitor |
|---|
All known targets
- GSK3B
- CDK1
- CDK5
- CCNB1
- CDK2
- GSK3A
- LCK
- Malaria Pfmrk
Mechanisms of action (all sources)
- cyclin-dependent kinase inhibitor
- GSK-3 inhibitor
- GSK3B INHIBITOR
- glycogen synthase kinase inhibitor
- CDK1 INHIBITOR
- Malaria Pfmrk INHIBITOR
- CCNB1 INHIBITOR
- CDK5 INHIBITOR
- GSK3A INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABL1
- FYN
- STK33
- STK3
- CHEK1
- CHEK2
- CSF1R
- SRC
- ROCK2
- ROCK1
- MARK3
- FLT3
- PLK4
- CDC42BPA
- PIM3
- PIM1
- PDPK1
- PAK6
- PAK5
- PAK4
- LIMK1
- LYN
- MAPK1
- MAPK3
- SYK
- MARK2
- BRSK2
- AURKB
- AURKA
- TGFBR1
- PDGFRB
- PIM2
- ULK2
- PHKG2
- ULK3
- PDGFRA
- PIN1
- PBK
- PASK
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CCNA1
- FXN
- VGFR2
- VGFR1
- TPO
- SMN
- SMCA2
- PRKN
- NTM1A
- NSD2
- KSYK
- ITPKC
- IL1B
- IFNB1
- HLAB
- GEMI
- ESRRA
- CCNA2
- DYR1A
- CSK21
- CP3A4
- CP2D6
- CP1A2
- CFTR
- CDK9
- CDK5R1
- CCNT2
- CCNT1
- CCNE2
- CCNE1
- CCNB3
- CCNB2
- VGFR3
Cross-references
Synonyms
- 9-Bromopaullone
- NSC-664704
- 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
- NSC664704
- MLS002702152
- CHEMBL296586
- 9-Bromo-7,12-dihydroindolo(3,2-d)(1)benzazepin-6(5H)-one
- Indolo[3,2-d][1]benzazepin-6(5H)-one,9-bromo-7,12-dihydro-
- QQUXFYAWXPMDOE-UHFFFAOYSA-N
- 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one
- 9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one
- 9-Bromo-7,12-dihydro-indolo-[3,2-d]-[1]benzazepin-6(5H)-one
- 9-bromo-7,12-dihydrobenzo[2,3]azepino[4,5-b]indol-6(5H)-one
- 9-Bromopaullone;NSC-664704
- Indolo[3,2-d][1]benzazepin-6(5H)-one, 9-bromo-7,12-dihydro-
- C16H11BrN2O
- NSC-664704(Kenpaullone)
- SR-01000075952
- Bromo Paullone
- MFCD02683595
- Kinome_3565
- Tocris-1398
- Kenpaullone, >=98%
- BiomolKI_000072
- Lopac-K-3888
- BiomolKI2_000076
- NCIMech_000735
- cid_3820
- Lopac0_000647
- SCHEMBL79889
- BDBM7266
- GTPL6000
- STO175
- T72H2BL53P
- CHEBI:92658
- DTXSID10161994
- EX-A702
- BCPP000195
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