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EMETINE
SynDRA canonical compound SYN0002448 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | RPS2 |
|---|
| Mechanism of action | Protein synthesis inhibitor |
|---|
All known targets
- RPS2
- ADRA1D
- ADRA2A
- ADRA2C
- Adra1a
- Adra1b
- RBBP9
Mechanisms of action (all sources)
- Protein synthesis inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB1
- ESR1
- SLC2A1
- S1PR1
- OPRM1
- NR1I2
- KCNH2
- GPR35
- ESR2
- HIF1A
- AGTR1
- NFE2L2
- MMP1
- MMP9
- MPG
- MTOR
- NEIL1
- NEIL2
- NPC1
- OPRK1
- NPSR1
- NPY1R
- NPY2R
- ADORA3
- NR3C1
- NTHL1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDM4E
- ADRA2B
- ITGAL
- IDH1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- A4
- MMP14
- NCOA3
- NOD1
- NOD2
- NR1H4
- NR5A2
- NSD2
- PPARD
- PRGR
- RARA
- RIPK2
- RORA
- S1PR3
- S1PR4
- SMAD2
- STAT1
- STK33
- SYK
- TBB5
- TF65
- TLR3
- TNF
- TP53
- TR10B
- TRFR
- VDR
- NCOA1
- MITF
- ANDR
- MEN1
- B2L11
- BARD1
- BRCA1
- CFTR
- CP19A
- CP2D6
- CREB1
- CSTA
- EPAS1
Drug classes
- Amebicides
- Anthelmintics
- Anti-Infective Agents
- Antinematodal Agents
- Antiparasitic Agents
- Antiprotozoal Agents
- Cathartics
- Central Nervous System Agents
- Emetics
- Enzyme Inhibitors
- Gastrointestinal Agents
- Peripheral Nervous System Agents
ATC classes
- P01A · AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
Cross-references
Synonyms
- emetine dihydrochloride
- emetine hydrochloride
- methylcephaeline
- ipecine
- (-)-Emetine
- cephaeline methyl ether
- emetin
- (-)-emetine
- 6',7',10,11-tetramethoxyemetan
- Cephaeline methyl ether
- Emetan, 6',7',10,11-tetramethoxy-
- Emetin
- Emetinum
- GNF-Pf-196
- NSC-33669
- TCMDC-125531
- Emetine hydrochloride
- MLS000028478
- SMR000058444
- NSC33669
- Emetine monohydrochloride
- Opera_ID_1460
- Cephaeline methyl ether HCl
- AC1O7FP4
- SCHEMBL636599
- CHEMBL513000
- DTXSID80424947
- MolPort-004-964-890
- Cephaeline methyl ether hydrochloride
- NSC752340
- AKOS024374935
- NSC-752340
- ST51014995
- Emetan,7',10,11-tetramethoxy-, dihydrochloride
- Q-100155
- 10-[((1R)-6,7-dimethoxy(1,2,3,4-tetrahydroisoquinolyl))methyl](10S,11aS,9R)-9- ethyl-2,3-dimethoxy-5,6,7,11a-tetrahydropiperidino[2,1-a]isoquinolin
- Methyl cephaeline
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