← SynDRA

DICLOXACILLIN

SynDRA canonical compound SYN0002444 — structure-anchored drug synonym record

All known targets

• ABCB11
• CHRM1
• CHRM2
• CHRM3
• HRH2
• PBP2
• PDE2A
• SLC6A3
• mecA
• pbp4
• pbpA
• pbpF

Mechanisms of action (all sources)

• bacterial cell wall synthesis inhibitor
• pbp4 INHIBITOR
• mecA INHIBITOR
• pbpA INHIBITOR
• PBP2 INHIBITOR
• pbpF INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• SLCO1B3
• SLCO1B1
• ACHE
• KDR
• SLC6A4
• SLC6A2
• SLC22A8
• SAMHD1
• PTGS1
• PGR
• PDE4A
• PDE3A
• OPRM1
• NFE2L2
• MAOA
• KCNH2
• ADORA3
• HTR2B
• HTR1A
• HRH3
• GMNN
• GLS
• F2
• ESR1
• DRD3
• DRD1
• CBX1
• AR
• ADRA2A
• ADRA1A
• TBXA2R

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ADA10
• ADA17
• CP2C9
• CP3A7
• MDR1

Drug classes

• Penicillin-class Antibacterial
• Anti-Bacterial Agents
• Anti-Infective Agents

ATC classes

• J01C · BETA-LACTAM ANTIBACTERIALS, PENICILLINS

Cross-references

• PubChem CID: 18381
• ChEMBL: CHEMBL893
• DrugBank: DB00485
• ChEBI: CHEBI:4511
• KEGG: D02137
• RxNorm: 3356
• Wikipedia: Dicloxacillin
• TTD: D0R2KJ
• LINCS BRD: BRD-K05673000

Synonyms

• DICLOXACILLIN SODIUM
• DYCILL
• DYNAPEN
• PATHOCIL
• dicloxacycline
• dicloxacillin sodium
• dicloxacillin sodium hydrate
• dicloxacillin sodium monohydrate
• Dicloxacilline
• Dicloxacilina
• BRL-1702
• R-13423
• Dichloroxacillin
• Diclossacillina
• Dicloxaciclin
• Dicloxacilin
• Dicloxacillinum
• Dicloxacycline
• Dycill
• Dynapen
• Maclicine
• Methyldichlorophenylisoxazolylpenicillin
• Pathocil
• Diclossacillina [DCIT]
• Dicloxacillin sodium
• BRL 1702
• Diclocil (TN)
• Dicloxacilina [INN-Spanish]
• Dicloxacilline [INN-French]
• Dicloxacillinum [INN-Latin]
• Dicloxacillin (USAN/INN)
• Dicloxacillin [USAN:INN:BAN]
• Dicloxacillin, Monosodium Salt, Mono-Hydrate
• R 13423
• COF19H7WBK
• CHEBI:4511
• Dicloxacillina
• Sodium, Dicloxacillin

Reported adverse events

• Hepatotoxicity
• Nausea
• Eosinophilia
• Pseudomembranous colitis
• Agranulocytosis