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PALIFOSFAMIDE
SynDRA canonical compound SYN0002427 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Mechanism of action | DNA alkylating agent |
|---|
All known targets
- DNMT1
- CYP2A6
- CYP3A7
- CYP2B6
- CYP2C19
- CYP2C8
- CYP2C9
- CYP2C18
- CYP3A4
- CYP3A5
- PTGS1
Mechanisms of action (all sources)
- DNA alkylating agent
- DNMT1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Drug classes
- Antineoplastic Agents, Alkylating
- Alkylating Activity
- Alkylating Drug
- Alkylating Agents
- Antineoplastic Agents
- Noxae
ATC classes
Cross-references
Synonyms
- Palifosfamida
- Ifosfamide mustard
- Isophosphamide mustard
- N,n'-bis-(2-chloroethyl)phosphoric acid
- IPM
- NSC-297900
- ZIO-201
- Isophosphoramide mustard
- Phosphorodiamidic acid, N,N'-bis(2-chloroethyl)-
- Ifosforamide mustard
- ZIO 201
- Palifosfamide [USAN]
- Palifosfamide [USAN:INN]
- N,N'-Bis(2-chloroethyl)phosphorodiamidic acid
- 6A4U6NN813
- PALIFOSFAMIDE [INN]
- PALIFOSFAMIDE [MART.]
- PALIFOSFAMIDE [WHO-DD]
- N,N'-Di-(2-chloroethyl)phosphorodiamidic acid
- N1,N2-Bis(2-chloroethyl)phosphoric acid diamide
- NSC297900
- bis[(2-chloroethyl)amino]phosphinic acid
- N,N'-BIS-(2-CHLOROETHYL)PHOSPHORIC ACID
- PALIFOSFAMIDE (MART.)
- bis((2-chloroethyl)amino)phosphinic acid
- palifosfamidum
- IPM-Lysine
- iphosphoramide mustard
- RefChem:858298
- Isophosphoramide Mustard-Lysine
- DTXCID80208648
- bis(2-chloroethylamino)phosphinic acid
- IPAM
- Isophosphoramide mustard;IPM;ZIO-201
- Palifosfamide?
- UNII-6A4U6NN813
- Palifosfamide (USAN/INN)
- C4H11Cl2N2O2P
- orb1302928
Reported adverse events
- Myelosuppression
- Hemorrhagic cystitis
- Hemorrhagic cyst
- Nephrotoxicity
- CNS toxicity
- Alopecia
- Constipation
- Dermatitis
- Fanconi syndrome
- Fatigue
- Hypertension
- Hypotension
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