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FAMCICLOVIR
SynDRA canonical compound SYN0002402 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | DNA polymerase inhibitor |
|---|
| Indication | cold sore | genitial herpes | shingles |
|---|
| Disease area | dental | infectious disease |
|---|
All known targets
Mechanisms of action (all sources)
- DNA polymerase inhibitor
- HSV UL30 INHIBITOR
- DNA directed DNA polymerase inhibitor
- TK1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- NPY2R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDM4E
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- HRH3
- HRH2
- HRH1
- HPGD
- HMGCR
- HDAC6
- HCAR2
- NPY1R
- NR3C1
- ADORA1
- NTSR1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- DNA Polymerase Inhibitors
- Anti-Infective Agents
- Antiviral Agents
- Enzyme Inhibitors
- Nucleic Acid Synthesis Inhibitors
- Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor
- Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
- S01A · ANTIINFECTIVES
- D06B · CHEMOTHERAPEUTICS FOR TOPICAL USE
Cross-references
Synonyms
- FAMVIR
- famcivir
- famcyclovir
- famtrex
- famvir
- BRL-42810
- NSC-758921
- Famvir
- FCV
- Famciclovirum
- Oravir
- IN1338
- Anti-Farnesyl Rabbit pAb
- Famciclovirum [INN-Latin]
- Famvir (TN)
- Famciclovir [USAN:BAN:INN]
- Famciclovir (JAN/USAN/INN)
- [2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate
- 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine
- BRL 42810
- CHEBI:4974
- Famciclovir (Famvir)
- NSC 758921
- QIC03ANI02
- NCGC00095133-01
- Famciclovir 100 microg/mL in Acetonitrile
- SMR000466375
- CAS-104227-87-4
- SR-01000759358
- UNII-QIC03ANI02
- Famciclovir [USAN:INN:BAN]
- HSDB 8121
- Famciclovir,(S)
- BRL42810
- Famciclovir, Bio-X
- MFCD00866964
- 1,3-diyl diacetate
Reported adverse events
- Headache
- Nausea
- Rash
- Pruritus
- Thrombocytopenia
- Urticaria
- Vomiting
- Palpitations
- Dizziness
- Fatigue
- Flatulence
- Leukopenia
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