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VALDECOXIB
SynDRA canonical compound SYN0002275 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
All known targets
- PTGS2
- CA12
- CA
- CYP2C19
- mtcA1
- ca1
- SLC6A2
- PTGS1
- NCE103
- MT-CO2
- MT-CO1
- HTR2B
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- PTGS2 INHIBITOR
- CA12 INHIBITOR
- LTF INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRB1
- ACHE
- HTR7
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDR
- KCNH2
- HTR6
- NPY1R
- HTR5A
- HTR3A
- HTR2C
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- HCAR2
- GIPR
- MMP9
- NPY2R
- GCGR
- NR1I2
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CAH12
- CP2C9
- CP2CJ
- ESRRA
- GLI3
- KSYK
- M4K2
- SYK
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Cyclooxygenase 2 Inhibitors
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Cross-references
Synonyms
- BEXTRA
- valecoxib
- Valdyn
- NSC-759846
- SC-65872
- Bextra
- Valdyn (previously kudeq)
- COX
- Kudeq
- Pfizer brand of valdecoxib
- Valdecoxib [USAN]
- ND-0214
- YM-974
- Valdecoxib (USAN/INN)
- 4-(Methyl-3-phenyl-isoxazol-4-yl)-benzenesulfonamide
- SC 65872
- valdecoxibum
- NSC 759846
- DTXCID4024226
- CHEBI:63634
- 4-[5-methyl-3-phenylisoxazol-4-yl]benzenesulfonamide
- RefChem:56405
- M01AH03
- MFCD00950568
- Valdecoxib-13C2, 15N
- NCGC00095129-01
- Valecoxib
- SMR000466327
- CAS-181695-72-7
- Parecoxib Impurity 2
- HSDB 7302
- Valdecoxib [USAN:INN:BAN]
- UNII-2919279Q3W
- Valdecoxib (Standard)
- Spectrum_001747
- 2aw1
- VALDECOXIB [MI]
- VALDECOXIB [INN]
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