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PENFLURIDOL
SynDRA canonical compound SYN0002270 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CACNA1G | DRD1 | DRD2 |
|---|
| Mechanism of action | T-type calcium channel blocker |
|---|
| Indication | schizophrenia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- CACNA1G
- DRD1
- DRD2
- ADRA1D
- HRH1
- OPRK1
- OPRD1
- HTR6
- HTR5A
- HTR2C
- HTR2B
- HTR2A
Mechanisms of action (all sources)
- T-type calcium channel blocker
- CACNA1G BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR7
- SLC6A2
- SLC6A3
- SLC6A4
- HDAC6
- POLK
- SMPD1
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ADRB2
- SYK
- SMAD3
- SMAD2
- RARA
- PPARD
- NSD2
- KSYK
- KCNK2
- KCNH2
- IFNG
- GPR32
- GLI3
- ESRRA
- ESR1
- CP3A7
- CP2D6
- CP2CJ
- CP2C9
- CP19A
- CASP7
- CASP3
- ATXN2
- ANDR
- TOR1A
Drug classes
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
ATC classes
Cross-references
Synonyms
- R-16341
- Micefal
- MCN-JR-16,341
- MCN-JR-16341
- NSC-759179
- R 16,341
- Semap
- 1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol
- TLP-607
- McN-JR-16,341
- 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
- Penfluridolum [INN-Latin]
- C28H27ClF5NO
- UNII-25TLU22Q8H
- EINECS 248-074-5
- BRN 1558826
- CHEMBL47050
- 25TLU22Q8H
- MDLAAYDRRZXJIF-UHFFFAOYSA-N
- 4-Piperidinol, 1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)-
- 4-Piperidinol,
- Hydroxamates
- Penfluridolum
- R 16341
- 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
- NSC 759179
- 4-Piperidinol, 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-
- NCGC00165865-01
- CAS-26864-56-2
- Longoperidol
- Penfluridol [USAN:INN:BAN]
- 1-(4,4-BIS(P-FLUOROPHENYL)BUTYL)-4-(4-CHLORO-.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)-4-PIPERIDINOL
- 1-[4,4-Bis(p-fluorophenyl)butyl]-4-(4-chloro-.alpha.,.alpha.,.alpha.-trifluoro-m-tolyl)-4-piperidinol
- MFCD00866714
- Semap (TN)
- PENFLURIDOL [MI]
- PENFLURIDOL [INN]
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