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PRIMIDONE
SynDRA canonical compound SYN0002233 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | GABRQ |
|---|
| Mechanism of action | GABA receptor antagonist |
|---|
| Indication | seizures |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- GABRA1
- GABRG2
- GABRB2
- GABRG3
- SCN3A
- SCN2A
- SCN1A
- SCN11A
- SCN10A
- SCN7A
- SCN8A
- GABRQ
Mechanisms of action (all sources)
- GABA receptor antagonist
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- MC3R
- OPRK1
- OPRD1
- NR3C1
- NR1I2
- NPY2R
- NPY1R
- NFE2L2
- MMP9
- MMP1
- MLNR
- MDH1
- MC5R
- MC4R
- ACHE
- HMGCR
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- OPRM1
- PDE3A
- PDE4D
- PDE5A
- USP1
- TSHR
- TDP1
- TBXAS1
- TBXA2R
- TARDBP
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anticonvulsants
- Central Nervous System Agents
- GABA Agents
- GABA Modulators
- Neurotransmitter Agents
- Anti-epileptic Agent
ATC classes
Cross-references
Synonyms
- MYSOLINE
- Mysoline
- desoxyphenobarbital
- lepimidin
- primaclone
- primacone
- Primidona
- Lepimidin
- Primaclone
- Resimatil
- NSC-41701
- Lepsiral
- Liskantin
- Cyral
- Desoxyphenobarbital
- Desoxyphenobarbitone
- Hexadiona
- Majsolin
- Midone
- Milepsin
- Misodine
- Misolyne
- Mizodin
- Mizolin
- Myidone
- Mylepsin
- Mylepsinum
- Mysedon
- Neurosyn
- Prilepsin
- Primacione
- Primacone
- Primakton
- Primidon
- Primidonum
- Primoline
- Prysoline
Reported adverse events
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