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TRIPROLIDINE
SynDRA canonical compound SYN0002225 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HRH1 |
|---|
| Mechanism of action | histamine receptor antagonist |
|---|
| Indication | allergic rhinitis |
|---|
| Disease area | allergy |
|---|
All known targets
Mechanisms of action (all sources)
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
- histamine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ADRA2B
- CHRM1
- SLC6A4
- OPRK1
- ADRA1A
- MC3R
- NFE2L2
- OPRD1
- OGG1
- NR3C1
- MAOA
- NR1I2
- NPY1R
- NPSR1
- NEIL2
- NEIL1
- OPRM1
- MPHOSPH8
- MBD4
- MPG
- MLNR
- MC4R
- MUTYH
- ADGRF1
- PDE3A
- SLC6A2
- TDP1
- TDG
- TBXA2R
- SMPD1
- SLCO1B3
- SLCO1B1
- SLC6A3
- SLC29A1
- LMNA
- SETD7
- SAMHD1
- S1PR1
- PTGS2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- CFTR
- CP2D6
- CP3A7
- GLI3
- JUN
- MDR1
- NF2L2
Drug classes
- Anti-Allergic Agents
- Histamine Agents
- Histamine Antagonists
- Histamine H1 Antagonists
- Neurotransmitter Agents
ATC classes
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
Cross-references
Synonyms
- ACTAHIST
- ACTIDIL
- ACTIFED
- ACTIFED W/ CODEINE
- ALLERFED
- CORPHED
- HISTAFED
- MYFED
- MYIDYL
- PSEUDOEPHEDRINE HYDROCHLORIDE AND TRIPROLIDINE HYDROCHLORIDE
- TRIACIN-C
- TRILITRON
- actidil
- triprolidin
- tripyrolidine
- triprolidine hydrochloride
- triprolidine HCl
- Triprolidina
- Actahist
- Allerfed
- Corphed
- Histafed
- Myfed
- Trilitron
- Triphed
- Actidil
- Actidilat
- Entra
- Myidyl
- Tripolidina
- Triprolidin
- Triprolidinum
- Venen
- Triprolidine HCL
- Triprolidine Monohydrochloride
- Triprolidine hydrochloride
- Triprolidine hydrochloride anhydrous
- T 6764
Reported adverse events
- Death
- Hypotension
- Sedation
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