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BENPERIDOL
SynDRA canonical compound SYN0002221 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Primary target(s) | DRD2 |
| Mechanism of action | Dopamine receptor antagonist |
| Indication | schizophrenia |
| Disease area | neurology/psychiatry |
All known targets
- DRD2
- DRD4
- DRD3
- HTR2A
- KCNH2
- SIGMAR1
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- DRD4 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HRH1
- ADRA1A
- HTR1A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- HTR2B
- OPRK1
- NR1I2
- CHRM2
- DRD1
- MLNR
- NR3C1
- NPY1R
- HTR2C
- MC3R
- LMNA
- HTR3A
- HRH3
- OPRD1
- ADORA1
- OPRM1
- PDE3A
- HRH2
- PGR
- PTGS2
- PTH1R
- RAPGEF3
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- PDE4D
- GLP1R
- HIF1A
- CHRNA4
- ADORA3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ACM1
- ACM4
- AHR
- ANDR
- CP2D6
- CP3A7
- ESRRA
- GLI3
- MDR1
Drug classes
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
ATC classes
Cross-references
Synonyms
- benzoperidol
- benzperidol
- frenactil
- frenactyl
- glianimon
- MCN-JR-4584
- NSC-170982
- R-4584
- Anquil
- Benquil
- Glianimon
- Frenactil
- Frenactyl
- Concilium
- Benzoperidol
- McN-JR 4584
- Benzperidol
- Glianimon mite
- R 4584
- Anquil (VAN)
- Benperidolo [DCIT]
- Benperidol hydrochloride
- Benzeridol
- Benperidolum [INN-Latin]
- Benperidol [USAN:INN:BAN]
- CB 8089
- UNII-97O6X78C53
- 8089 C. B.
- EINECS 218-172-2
- NSC 170982
- BRN 0900981
- 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl}-1h-benzo[d]imidazol-2(3h)-one
- 8089 C.B.
- C22H24FN3O2
- FEBOTPHFXYHVPL-UHFFFAOYSA-N
- NSC170982
- 2H-Benzimidazol-2-one, 1-[1-[4
- Benperidolo
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