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SPARFLOXACIN
SynDRA canonical compound SYN0002215 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | TOP2A |
|---|
| Mechanism of action | bacterial DNA gyrase inhibitor |
|---|
All known targets
- Bact gyrA
- Bact gyrB
- KCNH2
- Stap-coc parC
- TOP2A
- gyrA
- gyrB
- parC
- parE
Mechanisms of action (all sources)
- DNA gyrase inhibitor
- Bact gyrA; Bact gyrB MODULATOR
- Stap-coc parC MODULATOR
- parC INHIBITOR
- parE INHIBITOR
- gyrA INHIBITOR
- gyrB INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB1
- LCK
- NPY2R
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- KDR
- FLT1
- KAT2A
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC22A5
- SIGMAR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antineoplastic Agents
- Antitubercular Agents
- Enzyme Inhibitors
- Topoisomerase II Inhibitors
- Topoisomerase Inhibitors
ATC classes
- J01M · QUINOLONE ANTIBACTERIALS
Cross-references
Synonyms
- ZAGAM
- sparcin
- PD 131501
- AT-4140
- CI-978
- Sparfloxacine
- Esparfloxacino
- NSC-759641
- Spara
- Zagam
- SPFX
- Sparfloxacinum
- CP-103826
- PD-131501
- PD131501
- DRG-0143
- Esparfloxacino [INN-Spanish]
- Liposome-encapsulated sparfloxacin
- PD 1315-1
- RP-64206
- Respipac (TN)
- Sparfloxacin & RU 40555
- Sparfloxacine [INN-French]
- Sparfloxacinum [INN-Latin]
- Zagam (TN)
- Sparfloxacin, cis-isomer
- Sparfloxacin (JAN/USAN/INN)
- Sparfloxacin [USAN:BAN:INN:JAN]
- AT 4140
- CI 978
- CHEBI:9212
- Q90AGA787L
- NSC 759641
- MFCD00869619
- Parox
- CAS-110871-86-8
- SR-05000001521
- BRN 3658018
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