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N-METHYL-D-ASPARTIC ACID (NMDA)
SynDRA canonical compound SYN0002210 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | GRIN1 | GRIN2A | GRIN2B | GRIN2C | GRIN2D |
|---|
| Mechanism of action | glutamate receptor agonist |
|---|
All known targets
- GRIN1
- GRIN2A
- GRIN2B
- GRIN2C
- GRIN2D
Mechanisms of action (all sources)
- GRIN2C AGONIST
- GRIN2D AGONIST
- GRIN1 INHIBITOR
- GRIN2B INHIBITOR
- GRIN2A INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HPN
- HSD17B10
- SLCO1B3
- SLCO1B1
- SAMHD1
- POLI
- KDM4E
- KDM4A
- ALDH1A1
- CYP1A2
- GMNN
- EHMT2
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- NMDE1
- NMDE2
- NMDE3
- NMDZ1
- TNNC1
- TNNI3
- TNNT2
Cross-references
Synonyms
- (r)-2-(methylamino)succinic acid
- 2-methylamino-succinic acid
- N-methyl-daspartate
- 2-Methylamino-succinic acid(NMDA)
- N-Methyl-D-aspartic acid
- NMDA
- N-Methyl-D-aspartate
- N-Methylaspartate
- D-Aspartic acid, N-methyl-
- N-Me-D-Asp-OH
- (R)-2-(Methylamino)succinic acid
- NMDA (N-Methyl-D-aspartic acid)
- Methyl aspartic acid
- UNII-1903B9Q6PI
- N-Methyl aspartic acid
- (2R)-2-(methylamino)butanedioic acid
- 2-Methylamino-succinic acid
- BRN 1724431
- CHEMBL291278
- CHEBI:31882
- HOKKHZGPKSLGJE-GSVOUGTGSA-N
- 1903B9Q6PI
- N-Methyl-D-aspartic Acid, Hydrate
- AK-44365
- W-203368
- N-Methyl-D-aspartic acid, 98%
- N-methyl D-aspartic acid
- Nmda
- RefChem:1092483
- DTXCID6021082
- N-methyl D-aspartate
- (R)-2-Ethylbutannedioic acid
- MFCD00004226
- Me-D-Asp-OH
- N-Methyl-D-asparaginic Acid
- M03889
- SMR000326806
- (2R)-2-(methylazaniumyl)butanedioate
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