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TRICLOSAN
SynDRA canonical compound SYN0002201 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | DNMT1 |
|---|
| Mechanism of action | Enoyl-acyl-carrier protein reductase inhibitor |
|---|
| Indication | first-aid antiseptic |
|---|
| Disease area | infectious disease |
|---|
All known targets
- DNMT1
- CBR1
- ENR
- FabI
- HSPA5
- Malaria fabI
- fabI
- inhA
Mechanisms of action (all sources)
- Enoyl-acyl-carrier protein reductase inhibitor
- Malaria fabI BINDER
- fabI INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- ADORA3
- TTR
- ESR1
- ADRB2
- NR1I2
- SLC6A2
- NPY1R
- OPRK1
- OPRD1
- NR3C1
- NR1H4
- ADORA1
- NFE2L2
- OPRM1
- MC3R
- MAPT
- MAOA
- LMNA
- KCNH2
- IDH1
- MLNR
- PGR
- PDE3A
- PDE4D
- TP53
- THRB
- TDP1
- TBXA2R
- TARDBP
- SNCA
- SMAD3
- SLC6A4
- SLC6A3
- SAMHD1
- RXRA
- PTH1R
- PTGS2
- POLI
- HTR2C
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- PRGR
- KCNQ1
- KSYK
- MDM2
- MDM4
- NF2L2
- NSD2
- PHGDH
- PPARG
- RAPGEF4
- KCMB4
- RARA
- RGS4
- RPGF4
- RXFP1
- SC5A7
- SMAD2
- SYK
- TAAR1
- KCNE1
- KCMB2
- AK1C4
- CP3A7
- ANDR
- CASP3
- CASP7
- CP19A
- CP1A2
- CP2C9
- CP2CJ
- CP2D6
- ESRRA
- KCMB1
- GLI3
- HCRTR1
- HS90A
- HSPB1
- HTT
- IFNG
Drug classes
- Anti-Infective Agents
- Anti-Infective Agents, Local
- Antimetabolites
- Fatty Acid Synthesis Inhibitors
- Hypolipidemic Agents
- antibacterial agent
ATC classes
- D08A · ANTISEPTICS AND DISINFECTANTS
- D09A · MEDICATED DRESSINGS
Cross-references
Synonyms
- COLGATE TOTAL
- Clearskin
- Cloxifenol
- CH-3565
- DNDI1246774
- NSC-759151
- Aquasept
- Gamophen
- Innoxa
- Manusept
- Skinsan
- Stri-dex cleansing bar
- Tegusept
- Triclosan component of colgate total
- 2,4,4'-Trichloro-2'-hydroxydiphenyl ether
- Irgasan
- Cloxifenolum
- Triclosanum
- Irgasan DP300
- Stri-Dex Face Wash
- Lexol 300
- Stri-Dex Cleansing Bar
- Triclosanum [INN-Latin]
- DP-300
- Caswell No 186A
- C12H7Cl3O2
- UNII-4NM5039Y5X
- HSDB 7194
- CHEBI:164200
- Ether, 2'-hydroxy-2,4,4'-trichlorodiphenyl
- Phenyl ether, 2'-hydroxy-2,4,4'-trichloro-
- EINECS 222-182-2
- CHEMBL849
- EPA
- Cliniclean
- Sapoderm
- TCL
- Trisan
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