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PLUMBAGIN
SynDRA canonical compound SYN0002180 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Mechanism of action | anticancer agent |
|---|
All known targets
- EP300
- KAT2B
- Malaria DHOdehase
Mechanisms of action (all sources)
- EP300 INHIBITOR
- KAT2B INHIBITOR
- Malaria DHOdehase INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TST
- TRPA1
- NSD1
- CDC25A
- CDC25B
- CYP1A1
- CYP1A2
- CYP1B1
- AKT1
- RELA
- MAPK1
- MAPT
- POLK
- PTK2
- RAF1
- RECQL
- TOP1
- SMN1
- STAT3
- TDP1
- MAP2K7
- TP53
- USP1
- VDR
- MAP3K14
- KAT2A
- MAP2K1
- CYP2D6
- ALOX15
- APEX1
- BLM
- CASP1
- CASP7
- CYP2C19
- CYP2C9
- CYP3A4
- KDM4E
- EGFR
- ELANE
- ERBB2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- G3P
- HSPD1
- HSPE1
- MAOA
- MK01
- PE2R2
- PHGDH
- STK33
- UBP1
Drug classes
- Adjuvants, Immunologic
- Anticoagulants
- Antinematodal Agents
- Antineoplastic Agents, Phytogenic
- Cardiotonic Agents
- Contraceptive Agents
- anticancer agent
Cross-references
Synonyms
- PCUR-101
- NSC-236613
- NSC-688284
- Plumbagine
- 5-Hydroxy-2-methyl-1,4-naphthoquinone
- Plumbaein
- Plumbagone
- 2-Methyljuglone
- 5-hydroxy-2-methylnaphthalene-1,4-dione
- 5-Hydroxy-2-methyl-1,4-naphthalenedione
- 5-Hydroxy-2-methyl-[1,4]naphthoquinone
- 1,4-Naphthalenedione, 5-hydroxy-2-methyl-
- 2-Methyl-5-hydroxy-1,4-naphthoquinone
- UNII-YAS4TBQ4OQ
- NSC 688284
- NSC 236613
- CCRIS 6671
- YAS4TBQ4OQ
- EINECS 207-569-6
- BRN 1870475
- AI3-38055
- CHEBI:8273
- CHEMBL295316
- VCMMXZQDRFWYSE-UHFFFAOYSA-N
- 1,4-NAPHTHOQUINONE, 5-HYDROXY-2-METHYL-
- NSC688284
- 5-hydroxy-2-methyl-1,4-dihydronaphthalene-1,4-dione
- PCUR 101
- RefChem:863847
- PCUR101
- Synthetic Plumbagin PCUR-101
- MFCD00001682
- 5-Hydroxy-2-methyl-naphthalene-1,4-dione
- NSC236613
- ST069355
- Ophioxylin
- SR-05000002263
- Pumbagin
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