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PIRINIXIC ACID
SynDRA canonical compound SYN0002167 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | PPARA |
|---|
| Mechanism of action | PPAR receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- PPAR receptor agonist
- PPARA AGONIST
- PPARA INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PPARD
- PPARG
- RXRA
- ABCB11
- OPRD1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDM4E
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HRH2
- HRH1
- HPGD
- HMGCR
- NR3C1
- OPRM1
- OPRK1
- SIRT1
- VDR
- THRB
- TDP1
- TBXAS1
- TACR2
- TACR1
- SMN1
- SLC6A4
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- CP3A7
- CSTA
- ESRRA
- NR1I2
- NR5A2
- PHGDH
- RORB
Drug classes
- Anticholesteremic Agents
- Carcinogens
- Mutagens
- Peroxisome Proliferators
Cross-references
Synonyms
- Acide pirinixique
- Acido pirinixico
- NSC-310038
- WY-14643
- Wy 14643
- [4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid
- WY-14,643
- WY14643
- Wyeth 14,643
- Pirinixic acid [INN]
- WY-14643 (Pirinixic Acid)
- (4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio)acetic acid
- UNII-86C4MRT55A
- C14H14ClN3O2S
- CCRIS 133
- Acidum pirinixicum [INN-Latin]
- Acide pirinixique [INN-French]
- Acido pirinixico [INN-Spanish]
- NSC310038
- NSC 310038
- BRN 0759945
- ((4-Chloro-6-((2,3-dimethylphenyl)amino)-2-pyrimidinyl)thio)acetic acid
- Acetic acid, ((4-chloro-6-(
- pirinixic-acid
- Acidum pirinixicum
- DTXCID00290
- CHEBI:32509
- Wyeth-14643
- CXPTA
- WY14,643
- 4-chloro-6-(2,3-xylidinyl)-2-pyrimidinylthioacetic acid
- RefChem:863648
- WY 14643 (Pirinixic Acid)
- MFCD00191335
- NCGC00014702-03
- CAS-50892-23-4
- SR-01000597401
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