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EZOGABINE
SynDRA canonical compound SYN0002144 — structure-anchored drug synonym record
| Approval status | Approved · OTC |
|---|
| Primary target(s) | KCNQ4 |
|---|
| Mechanism of action | Potassium channel activator |
|---|
All known targets
- KCNQ3
- KCNQ2
- KCNQ4
- KCNQ5
- KCNQ1
- Kcnq2
Mechanisms of action (all sources)
- Potassium channel activator
- KCNQ1 OPENER
- KCNQ (Kv7) potassium channel opener
- KCNQ2 OPENER
- KCNQ3 OPENER
- KCNQ5 OPENER
- KCNQ4 OPENER
- KCNQ2 ACTIVATOR
- KCNQ3 MODULATOR
- KCNQ4 MODULATOR
- KCNQ5 MODULATOR
- KCNQ3 ACTIVATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CISD1
- HDAC6
- UGT1A1
- UGT1A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2C9
- CP2D6
- CP3A7
- KSYK
- SYK
Drug classes
- Anticonvulsants
- Central Nervous System Agents
- Membrane Transport Modulators
- Potassium Channel Openers
- Potassium Channel Opener
ATC classes
Cross-references
Synonyms
- POTIGA
- retigabine
- D-20443
- trobalt
- potiga
- KE 841
- GW 582892X
- WAY 143841
- Retigabine
- Retigabina
- Xen496
- AWD-21360
- AWD21-360
- D-23129
- GKE-841
- GW-582892X
- GW582892X
- WAY-143841
- XEN-496
- Potiga
- Trobalt
- Retigabine [USAN]
- ADD-230001
- KE-0201
- Ethyl 2-amino-4-((p-fluorobenzyl)amino)carbanilate
- Ethyl N-[2-amino-4-[(4-fluorophenyl)methylamino]phenyl]carbamate
- [2-Amino-4-[[(4-fluorophenyl)methyl]amino]phenyl]-carbamate
- D 23129
- XEN496
- ethyl (2-amino-4-((4-fluorobenzyl)amino)phenyl)carbamate
- CHEBI:68584
- N03AX21
- ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate
- retigabinum
- RefChem:139807
- DTXCID5087106
- Ezogabine [USAN]
- Retigabine [INN]
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