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DIACEREIN
SynDRA canonical compound SYN0002140 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | IL1B |
|---|
| Mechanism of action | Interleukin inhibitor |
|---|
| Indication | osteoarthritis |
|---|
| Disease area | rheumatology |
|---|
All known targets
- IL1B
- CASP3
- CASP7
- NAAA
- TTR
- gld-1
Mechanisms of action (all sources)
- Interleukin inhibitor
- IL1B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCC4
- PDE4D
- DRD3
- SLC29A1
- FTO
- MAOA
- KDM4E
- OPRM1
- KDM4A
- OPRK1
- OPRD1
- NR3C1
- NR1I2
- NPY1R
- MAPK1
- NFE2L2
- LMNA
- MLNR
- MC3R
- MBNL1
- MAPT
- PDE3A
- PGR
- IDH1
- SLCO1B1
- VDR
- USP2
- USP1
- TP53
- TDP1
- TBXA2R
- SMN1
- SLCO1B3
- SLC6A4
- PIN1
- SLC6A3
- SLC6A2
- SAMHD1
- PTGS2
- POLI
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CGAS
- CP3A7
- CTBP1
- ESRRA
- GSTO1
- HCRTR1
- HS90A
- HS90B
- NF2L2
- PIP4K2A
Drug classes
ATC classes
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Cross-references
Synonyms
- artrodar
- diacerhein
- diacetylrhein
- fisiodar
- Diacereine
- Diacereina
- Rhein diacetate
- Ac-203
- Artrodar
- Diacerhein
- Diacetylrhein
- Diora
- Verboril
- Zondar
- AC-201
- M-01AX21
- M01AX21
- NSC-758147
- SF-277
- Fisiodar
- 1,8-DIACETOXY-3-CARBOXYANTHRAQUINONE
- DIACERIN
- 4,5-Diacetylrhein
- Diacereinum [Latin]
- Diacereine [French]
- Diacereina [Spanish]
- UNII-4HU6J11EL5
- Diacerein [INN]
- C19H12O8
- EINECS 237-310-2
- BRN 2184909
- 4,5-diacetyloxy-9,10-dioxoanthracene-2-carboxylic acid
- MLS000028577
- 4HU6J11EL5
- 1,8-Diacetoxyanthraquinone-3-carboxylic acid
- Diacerein (INN)
- 4,5-diacetyloxy-9,10-dioxo-2-anthracenecarboxylic acid
- NCGC00018274-04
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